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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Cash flows from operating activities    
Net comprehensive loss $ (41,870,000) $ (49,075,000)
Adjustments to reconcile net loss and comprehensive loss to net cash used in operating activities:    
Amortization of debt issuance costs, debt discount, and non-cash interest expense 13,206,000 11,758,000
Change in fair value of freestanding and hybrid financial instruments designated at Fair Value Option 5,125,000 21,000
Stock-based compensation, vested and released restricted stock units and exercised stock options 2,112,000 3,318,000
Depreciation and amortization expenses 2,013,000 1,981,000
Amortization of operating lease - right-of-use-asset 375,000 311,000
Impairment loss on intangible assets 371,000  
Shares issued in exchange for services 171,000 823,000
Share in joint venture's loss 51,000  
(Gain) Loss on extinguishment of debt (3,697,000) 2,187,000
Changes in assets and liabilities    
Accounts receivable (88,000) (170,000)
Other receivable 386,000 (251,000)
Inventory (2,165,000) (2,124,000)
Prepaid expenses and other current assets (5,011,000) (1,560,000)
Other assets (17,000) (550,000)
Accounts payable (855,000) 902,000
Accrued liabilities (2,955,000) (360,000)
Operating lease liability (394,000) (315,000)
Total cash used in operating activities (33,242,000) (33,104,000)
Cash flows from investing activities    
Purchase of equipment   (77,000)
Purchase of intangible assets   (1,598,000)
Total cash used in investing activities   (1,675,000)
Cash flows from financing activities    
Proceeds from issuance of shares in At the Market offering, net of issuance and offering costs of $242 and $103 in 2023 and 2022, respectively 32,100,000 20,462,000
Proceeds from issuance of warrants in PIPE financing 1,236,000  
Investment from non-controlling interest 1,233,000  
Proceeds from issuance of preferred stock in PIPE financing, net of issuance cost of $12 611,000  
Payment of Tempesta Note (100,000) (100,000)
Repayment of insurance financing (853,000) (1,156,000)
Proceeds from notes payable with Streeterville   3,975,000
Total cash provided by financing activities 34,227,000 23,181,000
Effects of foreign exchange rate changes on assets and liabilities 15,000 16,000
Net increase (decrease) in cash 1,000,000 (11,582,000)
Cash at beginning of the year 5,469,000 17,051,000
Cash at end of the year 6,469,000 5,469,000
Supplemental schedule of cash flow information    
Cash paid for interest 35,000 23,000
Supplemental schedule of non-cash financing and investing activities    
First Insurance Financing 676,000 1,056,000
Lease modification 441,000 0
Umbrella Insurance Financing 110,000  
Recognition of operating lease - right-of-use asset and operating lease liability 30,000 365,000
Streeterville    
Supplemental schedule of non-cash financing and investing activities    
Warrants issued due to Royal Interest Global Amendment 59,000  
Streeterville | Preferred Stock    
Supplemental schedule of non-cash financing and investing activities    
Shares issued in exchange of notes payable and accrued interest 1,730,000 792,000
Iliad    
Supplemental schedule of non-cash financing and investing activities    
Warrants issued in exchange of Standstill 535,000  
Warrants issued due to Royal Interest Global Amendment 54,000  
Iliad | Common Stock    
Supplemental schedule of non-cash financing and investing activities    
Shares issued in exchange of notes payable and accrued interest 2,064,000 $ 10,472,000
Irving    
Supplemental schedule of non-cash financing and investing activities    
Warrants issued in exchange of Standstill 1,934,000  
Warrants issued due to Royal Interest Global Amendment 61,000  
Irving | Preferred Stock    
Supplemental schedule of non-cash financing and investing activities    
Shares issued in exchange of notes payable and accrued interest 2,201,000  
Irving | Common Stock    
Supplemental schedule of non-cash financing and investing activities    
Shares issued in exchange of notes payable and accrued interest $ 2,022,000