Summary of Significant Accounting Policies - Non-Controlling Interest (Details) $ in Thousands, € in Millions	3 Months Ended
	Mar. 31, 2023 EUR (€)	Mar. 31, 2023 USD ($)	Dec. 31, 2022
Increase in non-controlling interest due to additional investment from outsiders	€ 1.1	$ 1,230
Napo Therapeutics
Percentage of ownership interest by parent	88.00%	88.00%	90.00%
Private Investors
Percentage of ownership interest by non-controlling owners	12.00%	12.00%	10.00%