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CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
Series 1, Series 2 and Bridge warrant
Common Stock
Common stock - voting
Series 1, Series 2 and Bridge warrant
Additional paid-in capital
Series 1, Series 2 and Bridge warrant
Series 3 warrants
Common Stock
Common stock - voting
Series 3 warrants
Additional paid-in capital
Series 3 warrants
ELOC
Additional paid-in capital
ELOC
Private Investment in Public Entities
Common Stock
Common stock - voting
Private Investment in Public Entities
Additional paid-in capital
Private Investment in Public Entities
Underwriter Settlement Agreement
Noncontrolling Interest
Underwriter Settlement Agreement
Accumulated deficit
Underwriter Settlement Agreement
At The Market Offering
Common Stock
Common stock - voting
At The Market Offering
Additional paid-in capital
At The Market Offering
Registered public offering
Common Stock
Common stock - voting
Registered public offering
Additional paid-in capital
Registered public offering
Common Stock
Common stock - voting
Streeterville
Common Stock
Common stock - voting
Iliad
Common Stock
Common stock - voting
Common Stock
Common stock - non-voting
Additional paid-in capital
Streeterville
Additional paid-in capital
Iliad
Additional paid-in capital
Noncontrolling Interest
Accumulated deficit
Accumulated other comprehensive loss
Streeterville
Iliad
Total
Beginning Balance at Dec. 31, 2020                                                     $ 184,101,000   $ (166,899,000)       $ 17,202,000
Beginning Balance (in shares) at Dec. 31, 2020                                             506,765 2,120,786                  
Increase (decrease) in Stockholders' Equity (Deficit)                                                                  
Issuance of common stock                   $ 1,751,000 $ 1,751,000         $ 8,595,000 $ 8,595,000   $ (23,232,000) $ (23,232,000)                          
Issuance of common stock (In shares)                 9,679           39,086     53,711                              
Shares issued in exchange of notes payable and accrued interest                                                   $ 2,982,000           $ 2,982,000  
Shares issued in exchange of notes payable and accrued interest (in shares)                                           7,843                      
Shares issued in extinguishment of Exchange Note 2                                                     2,516,000           2,516,000
Shares issued in extinguishment of Exchange Note 2 (in shares)                                             6,283                    
Shares issued to other third party for services                                                     16,000           16,000
Shares issued to other third party for services (in shares)                                             75                    
Shares issued on exercise of warrants   $ 2,034,000 $ 2,034,000   $ 1,776,000 $ 1,776,000                                                      
Shares issued on exercise of warrants (in shares) 18,447     2,759                                                          
Shares issued upon exercise of stock options                                                     4,000           4,000
Shares issued upon exercise of stock options (in shares)                                             42                    
Shares issued on conversion of Napo merger common shares (in shares)                                             10                    
Acquisition of a subsidiary                                                       $ 247,000         247,000
Issuance of warrants             $ 124,000 $ 124,000                                                  
Stock-based compensation                                                     3,974,000           3,974,000
Net loss                       $ (5,000) $ (52,595,000) $ (52,600,000)                                     (52,600,000)
Translation adjustments                                                                 0
Ending Balance at Dec. 31, 2021                                                     231,105,000 242,000 (219,494,000)       11,853,000
Ending Balance (in shares) at Dec. 31, 2021                                             644,700 2,120,786                  
Increase (decrease) in Stockholders' Equity (Deficit)                                                                  
Issuance of common stock                               $ 20,462,000 $ 20,462,000                                
Issuance of common stock (In shares)                             923,164                                    
Shares issued in exchange of notes payable and accrued interest                                                 $ 5,056,000 $ 6,207,000         $ 5,056,000 $ 6,207,000  
Shares issued in exchange of notes payable and accrued interest (in shares)                                         310,196 235,461                      
Shares issued to Synworld for services                                                     800,000           800,000
Shares issued to Synworld for services (in shares)                                             45,896                    
Shares issued to other third party for services                                                     23,000           23,000
Shares issued to other third party for services (in shares)                                             20,151                    
Shares issued upon vesting and release of restricted stock units                                                     100,000           100,000
Shares issued upon vesting and release of restricted stock units (in shares)                                             2,516                    
Stock-based compensation                                                     3,218,000           3,218,000
Net loss                                                       (941,000) (47,454,000)       (48,395,000)
Translation adjustments                                                           $ (680,000)     (680,000)
Ending Balance at Dec. 31, 2022                                                     $ 266,971,000 $ (699,000) $ (266,948,000) $ (680,000)     $ (1,356,000)
Ending Balance (in shares) at Dec. 31, 2022                                             2,182,084 2,120,786