Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2022

Stock-Based Compensation

Summary of incentive plan activity

				Weighted		Weighted Average
	Shares	Stock		Average		Remaining	Aggregate
	Available	Options	RSUs	Stock Option		Contractual Life	Intrinsic
(in thousands, except share and per share data)	for Grant	Outstanding	Outstanding	Exercise Price		(Years)	Value*
Outstanding at January 1, 2021	2,652	20,229	5	$	950.90	8.71	$	364
Additional shares authorized	25,358	—	—		—			—
Options granted	(13,547)	13,547	—		405.45			—
Options exercised	—	(42)	—		100.35			—
Options canceled	448	(448)	—		2,285.32			—
RSUs granted	(6,494)	—	6,494		—			—
RSUs vested and released	—	—	—		—			—
RSUs cancelled	—	—	—		—			—
Outstanding at December 31, 2021	8,417	33,286	6,499	$	707.97	8.35	$	3
Additional shares authorized	151,079	—	—		—			—
Options granted	(44)	44	—		23.46			—
Options exercised	—	—	—		—			—
Options canceled	5,251	(5,251)	—		418.34			—
RSUs granted	(41,725)	—	41,725		—			—
RSUs vested and released	—	—	(2,516)		—			—
RSUs cancelled	—	—	(843)		—			—
Outstanding at December 31, 2022	122,978	28,079	44,865	$	592.73	7.19	$	—
Exercisable at December 31, 2022		26,102		$	614.51	7.11	$	—
Vested and expected to vest at December 31, 2022		27,901		$	594.38	7.18	$	—

*Fair market value of Jaguar stock on December 31, 2022 was $6.52 per share.

Summary of stock-based compensation expense

	Year Ended
	December 31,
(in thousands)	2022		2021
Research and development expense	$	1,263	$	1,319
Sales and marketing expense		267		319
General and administrative expense		1,788		2,336
Total	$	3,318	$	3,974

Employee stock options

Stock-Based Compensation

Schedule of estimated grant-date fair value of stock options calculated using the Black-Scholes option-pricing model

	Year Ended
	December 31,
	2022	2021
Volatility	164.0%	163.8 - 164.0 %
Expected term (years)	5.0	5.0
Risk-free interest rate	3.2%	0.5 - 1.2 %
Expected dividend yield	—	—