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Stockholders' Equity (Details)
6 Months Ended
Sep. 03, 2021
Jun. 30, 2022
Vote
shares
Dec. 31, 2021
shares
Shares of common stock reserved for issuance      
Options issued and outstanding   2,319,718 2,464,803
Options available for grant under stock option plans   697,974 631,270
RSUs awards issued and outstanding   3,376,086 487,456
Warrants issued and outstanding   563,451 563,451
Total   7,074,762 4,185,269
Number of voting rights entitled for each share of common stock held | Vote   1  
Reverse stock split ratio 33.33    
2014 Plan      
Shares of common stock reserved for issuance      
Options issued and outstanding   2,319,595 2,348,076
Options available for grant under stock option plans   119,464 619,480
Minimum      
Shares of common stock reserved for issuance      
Reverse stock split ratio 0.5    
Maximum      
Shares of common stock reserved for issuance      
Reverse stock split ratio 0.05    
Inducement options issued and outstanding      
Shares of common stock reserved for issuance      
Options issued and outstanding   117,533 38,289
Blank check preferred stock      
Shares of common stock reserved for issuance      
Common stock, shares authorized   4,475,074  
Common Stock      
Shares of common stock reserved for issuance      
Common stock, shares authorized   204,475,074  
Common Stock | Common stock - voting      
Shares of common stock reserved for issuance      
Common stock, shares authorized   150,000,000 150,000,000
Common Stock | Common stock - non-voting      
Shares of common stock reserved for issuance      
Common stock, shares authorized   50,000,000 50,000,000
Convertible non-voting common stock      
Shares of common stock reserved for issuance      
Reverse stock split ratio   1