CONSOLIDATED STATEMENTS OF CASH FLOWS	12 Months Ended
	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)
Cash flows from operating activities
Net loss	$ (33,809,000)	$ (38,539,000)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization expense	1,727,000	1,737,000
Impairment of indefinite-lived intangible assets	0	4,000,000
Interest paid on the conversion of debt to equity	611,000
Loss on recourse obligation on secured borrowing	15,000
Loss on extinguishment of debt and conversion of Series D perpetual preferred stock	1,864,000	4,941,000
Amortization of operating lease right-of-use-assets	553,000	191,000
Expense on modification of warrants	86,000
Series B convertible preferred stock inducement expense	1,647,000
Series 3 warrants issued as an inducement to exercise equity-classified Series 1, Series 2 and Bridge warrants	3,696,000
Stock-based compensation	2,824,000	2,989,000
Issuance of common stock in exchange for services	984,000	140,000
Issuance of common stock in Tempesta settlement agreement		49,000
Issuance of warrants and common stock in underwriter settlement agreement	76,000
Issuance of common stock as consideration paid under the Oasis Capital Equity Purchase Agreement	33,000
Tempesta settlement note expense		550,000
Amortization of debt issuance costs and debt discount	2,670,000	5,157,000
Shares issued to Atlas for settlement of Trial Delay Fee	612,000
Shares issued on conversion of warrants of Atlas for settlement of Trial Delay Fee	1,904,000
Change in fair value of financial instruments	2,696,000	(1,010,000)
Changes in assets and liabilities
Accounts receivable	(2,840,000)	(696,000)
Other receivable	(26,000)	(8,000)
Inventory	(653,000)	1,213,000
Prepaid expenses and other current assets	(955,000)	(247,000)
Other non-current assets	893,000	109,000
Operating lease liabilities	(337,000)	(133,000)
Deferred rent		222,000
Accounts payable	(743,000)	(63,000)
Accrued expenses	1,194,000	(1,059,000)
Total cash used in operating activities	(15,278,000)	(20,457,000)
Cash flows from investing activities
Purchase of equipment	(7,000)
Total cash used in investing activity	(7,000)
Cash flows from financing activities
Proceeds from issuance of notes payable, net of issuance costs of $50 and debt discount	12,300,000
Proceeds from receivables secured borrowing, net of debt discount and issuance costs of $640	7,057,000
Proceeds from issuance of short-term notes payable		5,050,000
Repayment of short-term notes payable		(5,050,000)
Repayment of notes payable	(406,000)	(100,000)
Repayment of insurance premium financing	(681,000)
Repayment of receivables secured borrowing	(6,207,000)
Proceeds from issuance of common stock		2,878,000
Payment of underwriting discounts, commissions and other associated offering costs		(65,000)
Payments of deferred offering costs	(142,000)
Total cash provided by financing activities	19,492,000	21,772,000
Net increase in cash and restricted cash	4,207,000	1,315,000
Cash and restricted cash at beginning of period	3,883,000	2,568,000
Cash and restricted cash at end of period	8,090,000	3,883,000
Supplemental schedule of cash flow information
Cash paid for interest	757,000	142,000
Supplemental schedule of non-cash financing and investing activities
Insurance premium financing	776,000
Accretion to redemption value of Series A contingently redeemable convertible preferred stock	(1,332,000)
Common stock issued as redemption of Series D perpetual preferred stock	6,575,000
Cash	8,090,000	3,495,000
Restricted cash		388,000
Cash and restricted cash at end of period	8,090,000	3,883,000
PoC Capital, LLC
Supplemental schedule of non-cash financing and investing activities
Shares issued to PoC Capital in payment of contracted research fees	437,000
Private Investment in Public Entities March 2018
Cash flows from financing activities
Proceeds from issuance of common stock in PIPE financing, net of issuance costs	668,000	1,500,000
2019 Bridge Note Warrants
Cash flows from financing activities
Proceeds from shares issued on exercise of Oasis Capital an Equity Purchase Agreement put options, net of issuance costs of $13	5,797,000
Notes payable
Supplemental schedule of non-cash financing and investing activities
Common stock issued as redemption of notes payable and related interest	6,165,000	15,345,000
Issuance of warrants		5,006,000
At The Market Offering
Cash flows from financing activities
Proceeds from issuance of common stock	1,281,000
Payment of underwriting discounts, commissions and other associated offering costs	(40,000)
PIPE Financing Warrants, Dec 2019
Cash flows from financing activities
Proceeds from issuance of warrants		1,500,000
Bridge Note Warrants
Supplemental schedule of non-cash financing and investing activities
Reclassification of warrants from liability to equity		4,259,000
Series 1 warrants
Supplemental schedule of non-cash financing and investing activities
Deemed dividend attributable to preferred stock		522,000
March 2019 letter of credit warrant
Supplemental schedule of non-cash financing and investing activities
Issuance of warrants		116,000
Reclassification of warrants from liability to equity		71,000
Series 1 Warrants via Put option Oct 2019
Cash flows from financing activities
Proceeds from issuance of warrants		1,750,000
Pre-funded Warrants
Cash flows from financing activities
Issuance costs from shares issued on underwriter settlement agreement		(65,000)
Series 1, Series 2, and 2019 Bridge Note warrants May 2020
Cash flows from financing activities
Payment of underwriting discounts, commissions and other associated offering costs	(486,000)
Series 1 and Series 2 warrants
Supplemental schedule of non-cash financing and investing activities
Deemed dividend attributable to preferred stock	856,000
Series 3 warrants
Supplemental schedule of non-cash financing and investing activities
Shares Issued	6,057,000
Underwriter Settlement Agreement
Cash flows from financing activities
Issuance costs from shares issued on underwriter settlement agreement	(185,000)
Common Stock To Oasis Put Exercise
Cash flows from financing activities
Payment of underwriting discounts, commissions and other associated offering costs	(13,000)
Proceeds from shares issued on exercise of Oasis Capital an Equity Purchase Agreement put options, net of issuance costs of $13	10,000
Series B convertible preferred stock
Cash flows from financing activities
Payment of underwriting discounts, commissions and other associated offering costs		(875,000)
Proceeds from issuance of common stock in PIPE financing, net of issuance costs		4,240,000
Supplemental schedule of non-cash financing and investing activities
Deemed dividend attributable to preferred stock		4,240,000
Shares Issued	476,000	2,128,000
Conversion of Series B-2 convertible preferred stock into common stock	476,000
Series A convertible preferred stock
Supplemental schedule of non-cash financing and investing activities
Deemed dividend attributable to preferred stock	1,332,000	895,000
Accretion to redemption value of Series A contingently redeemable convertible preferred stock	1,332,000	894,000
Extinguishment of Series A redeemable convertible preferred stock	11,227,000
Series B-2 convertible preferred stock
Supplemental schedule of non-cash financing and investing activities
Conversion of Series B-2 convertible preferred stock into common stock	1,236,000
Series B-2 convertible preferred stock | Pre-funded Warrants | Private Investment In Public Entities November 2019 offering
Cash flows from financing activities
Proceeds from issuance of convertible preferred stock		1,778,000
Series C perpetual preferred stock
Supplemental schedule of non-cash financing and investing activities
Deemed dividend attributable to preferred stock	2,521,000
Shares Issued	4,717,000
Stock dividend attributable to Series C perpetual preferred stock	130,000
Series D perpetual preferred stock
Supplemental schedule of non-cash financing and investing activities
Shares Issued	$ 6,404,000
Class A units
Cash flows from financing activities
Proceeds from issuance of common stock		2,249,000
Payment of underwriting discounts, commissions and other associated offering costs		(875,000)
Class B units
Cash flows from financing activities
Payment of underwriting discounts, commissions and other associated offering costs		(1,635,000)
Class A and B units | Series 1 warrants
Cash flows from financing activities
Proceeds from issuance of warrants		5,026,000
Class A and B units | Series 2 warrants
Cash flows from financing activities
Proceeds from issuance of warrants		$ 5,026,000