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Stock Incentive Plans - Summary of Stock Incentive Plans (Details) - USD ($)
9 Months Ended 12 Months Ended
May 12, 2015
Sep. 30, 2020
Sep. 30, 2019
Dec. 31, 2019
Sep. 30, 2020
Jun. 16, 2020
Dec. 31, 2019
Stock Based Compensation              
Option outstanding   4,516,424   3,902,675 4,516,424   3,902,675
Shares available for grant   651,739   479,829 651,739   479,829
Shares Available for Grant              
Beginning balance (in shares)   479,829          
Ending balance (in shares)   651,739   479,829      
Stock Options Outstanding              
Beginning balance (in shares)   3,902,675          
Options granted (in shares)   953,318          
Options exercised (in shares)   (555)          
Options cancelled (in shares)   (338,999)          
Options canceled not rolled back into the 2013 Plan (in shares)   (15)          
Ending balance (in shares)   4,516,424   3,902,675      
RSUs Outstanding              
Beginning balance (in shares)   5,613          
Ending balance (in shares)   5,613   5,613      
Weighted Average Stock Option Exercise Price              
Beginning balance (in dollars per share)   $ 5.20          
Options granted (in dollars per share)   0.44          
Options exercised (in dollars per share)   0.45          
Options cancelled (in dollars per share)   4.11          
Ending balance (in dollars per share)   $ 4.28   $ 5.20      
Weighted Average Remaining Contractual Life (Years)              
Weighted Average Remaining Contractual Life (Years)   8 years 11 months 19 days   9 years 6 months 22 days      
Options vested, exercisable and expected to vest              
Options exercised (in shares)   (555)          
Weighted average grant date fair value of stock options granted (in dollars per share)   $ 0.39 $ 1.57        
Number of options vested (in shares)   1,065,190 496,467        
Weighted average fair value of options vested on grant date   $ 2.12 $ 132.26        
Common Stock, Capital Shares Reserved for Future Issuance         13,945,846   27,200,498
Inducement options issued and outstanding              
Stock Based Compensation              
Option outstanding   33,392   74 33,392   74
Stock Options Outstanding              
Beginning balance (in shares)   74          
Ending balance (in shares)   33,392   74      
2013 Plan | Stock options              
Stock Based Compensation              
Option shares outstanding         384    
Stock Options Outstanding              
Options granted (in shares)   0          
2014 Plan              
Stock Based Compensation              
Option outstanding   4,483,106   3,902,675 4,483,106   3,902,675
Shares available for grant   479,829   479,829     479,829
Shares Available for Grant              
Beginning balance (in shares)   479,829          
Additional shares authorized (in shares)   786,229          
Options granted (in shares)   (953,318)          
Options cancelled (in shares)   338,999          
Ending balance (in shares)       479,829      
Stock Options Outstanding              
Beginning balance (in shares)   3,902,675          
Ending balance (in shares)   4,483,106   3,902,675      
RSUs Outstanding              
Beginning balance (in shares)   5,613          
Ending balance (in shares)   5,613   5,613      
Options vested, exercisable and expected to vest              
Options vested and exercisable (in shares)         1,870,808    
Options vested and exercisable (in dollars per share)         $ 8.14    
Options vested and exercisable (in years)   8 years 10 months 10 days          
Options vested and expected to vest (in shares)         4,170,443    
Options vested and expected to vest (in dollars per share)         $ 4.53    
Options vested and expected to vest (in years)   8 years 11 months 16 days          
2014 Plan | Stock options              
Stock Based Compensation              
Increase in share reserve based on outstanding number of shares (as a percent) 5.00%            
Option outstanding   4,482,722     4,482,722    
Shares available for grant   185,057     185,057    
Shares Available for Grant              
Ending balance (in shares)   185,057          
Stock Options Outstanding              
Ending balance (in shares)   4,482,722          
2020 New Employee Inducement Award Plan              
Stock Based Compensation              
Option outstanding   33,318     33,318    
Shares available for grant   466,682     466,682    
Shares Available for Grant              
Ending balance (in shares)   466,682          
Stock Options Outstanding              
Ending balance (in shares)   33,318          
Options vested, exercisable and expected to vest              
Common Stock, Capital Shares Reserved for Future Issuance           500,000  
Common Stock              
Options vested, exercisable and expected to vest              
Share Price         $ 0.29