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Stock Incentive Plans - Summary of Stock Incentive Plans (Details) - USD ($)
3 Months Ended 12 Months Ended
May 12, 2015
Mar. 31, 2020
Mar. 31, 2019
Dec. 31, 2019
Mar. 31, 2020
Stock Based Compensation          
Option outstanding   4,508,021   3,902,675 4,508,021
Shares available for grant   160,697   479,829 160,697
Shares Available for Grant          
Beginning balance (in shares)   479,829      
Ending balance (in shares)   160,697   479,829  
Stock Options Outstanding          
Beginning balance (in shares)   3,902,675      
Ending balance (in shares)   4,508,021   3,902,675  
RSUs Outstanding          
Beginning balance (in shares)   5,613      
Ending balance (in shares)   5,613   5,613  
Options vested, exercisable and expected to vest          
Weighted average grant date fair value of stock options granted (in dollars per share)   $ 0.41 $ 17.50    
Number of options vested (in shares)   333,926 7,480    
Weighted average fair value of options vested on grant date   $ 2.38 $ 132.81    
Inducement options issued and outstanding          
Stock Based Compensation          
Option outstanding   74   74 74
Stock Options Outstanding          
Beginning balance (in shares)   74      
Ending balance (in shares)   74   74  
2013 Plan | Stock options          
Stock Based Compensation          
Option shares outstanding         384
Stock Options Outstanding          
Options granted (in shares)   0      
2014 Plan          
Stock Based Compensation          
Option outstanding   4,508,021   3,902,675 4,508,021
Shares available for grant   160,697   479,829 160,697
Shares Available for Grant          
Beginning balance (in shares)   479,829      
Additional shares authorized (in shares)   286,229      
Options granted (in shares)   (810,000)      
Options cancelled (in shares)   204,639      
Ending balance (in shares)   160,697   479,829  
Stock Options Outstanding          
Beginning balance (in shares)   3,902,675      
Options granted (in shares)   810,000      
Options cancelled (in shares)   (204,639)      
Options canceled not rolled back into the 2013 Plan (in shares)   (15)      
Ending balance (in shares)   4,508,021   3,902,675  
RSUs Outstanding          
Beginning balance (in shares)   5,613      
Ending balance (in shares)   5,613   5,613  
Weighted Average Stock Option Exercise Price          
Beginning balance (in dollars per share)   $ 5.20      
Options granted (in dollars per share)   0.45      
Options cancelled (in dollars per share)   3.40      
Ending balance (in dollars per share)   $ 4.43   $ 5.20  
Weighted Average Remaining Contractual Life (Years)          
Weighted Average Remaining Contractual Life (Years)   9 years 4 months 2 days   9 years 6 months 22 days  
Options vested, exercisable and expected to vest          
Options vested and exercisable (in shares)         1,230,522
Options vested and exercisable (in dollars per share)         $ 11.01
Options vested and exercisable (in years)   8 years 11 months 9 days      
Options vested and expected to vest (in shares)         3,968,171
Options vested and expected to vest (in dollars per share)         $ 4.83
Options vested and expected to vest (in years)   9 years 3 months 26 days      
Options exercised (in shares)   0      
Aggregate Intrinsic Value ,outstanding         $ 27,832
2014 Plan | Stock options          
Stock Based Compensation          
Increase in share reserve based on outstanding number of shares (as a percent) 2.00%        
Common Stock          
Options vested, exercisable and expected to vest          
Share Price         $ 0.48