Stock Based Compensation (Tables)

12 Months Ended

Dec. 31, 2019

Stock Based Compensation

Summary of incentive plan activity

				Weighted		Weighted Average
	Shares	Stock		Average		Remaining	Aggregate
	Available	Options	RSUs	Stock Option		Contractual Life	Intrinsic
	for Grant	Outstanding	Outstanding	Exercise Price		(Years)	Value*
Outstanding at December 31, 2018	2,327	42,059	5,613	$	406.36	9.24	$	—
Additional shares authorized	4,338,197	—	—		—	—
Options granted	(4,481,764)	4,481,764	—		1.68	—		—
Options canceled	621,069	(621,148)	—		5.51	—		—
Outstanding at December 31, 2019	479,829	3,902,675	5,613	$	5.20	9.56	$	—
Exercisable at December 31, 2019		904,051		$	13.77	9.47	$	—
Vested and expected to vest at December 31, 2019		3,364,438		$	5.69	9.55	$	—

*    Fair market value of Jaguar stock on December 31, 2019 was $0.80 per share.

Summary of stock-based compensation expense

	Year Ended
	December 31,
	2019		2018
Research and development expense	$	868,603	$	579,641
Sales and marketing expense		160,837		96,730
General and administrative expense		1,959,104		1,347,503
Total	$	2,988,544	$	2,023,874

Employee stock options

Stock Based Compensation

Schedule of estimated grant-date fair value of stock options calculated using the Black-Scholes option-pricing model

	Year Ended
	December 31,
	2019		2018
Weighted-average volatility	143.1 - 145.9	%	87.4 - 105.9	%
Weighted-average expected term (years)	5.0 - 5.8		5.1 - 5.8
Risk-free interest rate	1.5 - 1.9	%	2.6 - 2.9	%
Expected dividend yield	—		—