CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)	3 Months Ended			9 Months Ended		12 Months Ended
	Sep. 30, 2019	Dec. 31, 2018	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018	Dec. 31, 2018
Cash flows from operating activities
Net loss	$ (7,555,065)		$ (6,138,352)	$ (32,580,053)	$ (19,492,172)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization expense				1,304,946	989,116
Impairment of indefinite-lived intangible assets	0		0	4,000,000	0
Interest paid on the conversion of debt to equity					21,275
Common stock issued in exchange for services rendered					6,425
Loss on extinguishment of debt	335,753			4,940,911
Amortization of operating lease right-of-use-assets				554,017
Stock-based compensation				1,982,985	1,416,791
Amortization of debt issuance costs and debt discount				5,032,214	1,461,133
Change in fair value of warrants, conversion option and derivative liability				(1,002,865)	(178,461)
Changes in assets and liabilities.
Accounts receivable				(597,848)	(561,012)
Other receivable				6,118	(175,009)
Inventory				1,020,040	(477,217)
Prepaid expenses and other current assets				(465,610)	(635,622)
Deferred offering costs					(1,255,554)
Other non-current assets					(289,828)
Deferred collaboration revenue					(177,389)
Operating lease liabilities				(346,679)	52,665
Accounts payable				(662,163)	(904,577)
Accrued expenses				(503,526)	2,370,682
Total cash used in operating activities				(17,317,513)	(17,828,754)
Cash flows from investing activities
Purchase of equipment					(6,527)
Total cash used in investing activities					(6,527)
Cash flows from financing activities
Proceeds from issuance of long-term debt					2,310,000
Repayment of notes payable				(100,000)	(1,689,200)
Proceeds from issuance of convertible debt					500,000
Proceeds from issuance of common stock through a stock purchase agreement with a private investor					1,305,774
Proceeds from the issuance of common stock in a private investment in public entities with existing investors					750,100
Fractional common shares repurchased					(30)
Proceeds from issuance of short-term notes payable				5,050,000
Repayment of short-term notes payable				(5,050,000)
Proceeds from the issuance of common stock, March 2019				266,266
Total cash provided by financing activities				16,818,856	17,801,543
Net increase (decrease) in cash				(498,657)	(33,738)
Cash at beginning of period		$ 726,129		2,568,191	759,867	$ 759,867
Cash at end of period	2,069,534	$ 2,568,191	$ 726,129	2,069,534	726,129	$ 2,568,191
Supplemental disclosure of cash flow information
Interest paid on long-term debt					$ 19,344
Supplemental schedule of non-cash financing and investing activities
Common stock issued in exchange for CVP Exchange Note 1 principal and related interest				6,672,950
Common stock issued in payment of accrued interest on Kingdon notes payable				446,729
Common stock issued in payment of CVP Note Payable principal and related interest				8,224,923
Common stock issued upon conversion of Series B convertible preferred stock				1,831,193
Reclassification of warrants from liability to equity				4,259,327
September 2018 L2 convertible note payable
Supplemental schedule of non-cash financing and investing activities
Issuance of warrants with short-term Notes Payable					118,148
Issuance of common stock					$ 48,000
Private Investment in Public Entities July 2019
Cash flows from financing activities
Proceeds from issuance of convertible preferred stock				3,875,778
Private Investment in Public Entities March 2018
Cash flows from financing activities
Proceeds from the issuance of common stock					5,000,000
Proceeds from the issuance of convertible preferred stock, March 2018					9,000,002
Proceeds from issuance of common stock, January to April 2019
Cash flows from financing activities
Proceeds from the issuance of common stock				2,602,896
Private Investment in Public Entities July 2018
Cash flows from financing activities
Proceeds from the issuance of common stock					624,897
Jaguar Notes Payable
Supplemental schedule of non-cash financing and investing activities
Common stock issued as redemption of notes payable and related interest					1,153,408
Napo convertible debt
Supplemental schedule of non-cash financing and investing activities
Common stock issued as redemption of notes payable and related interest					1,638,546
Series 1 warrants
Supplemental schedule of non-cash financing and investing activities
Deemed dividend				252,106
Series 1 warrants | Private Investment in Public Entities July 2019
Cash flows from financing activities
Proceeds from the issuance of Warrants in Class A and B Units, July 2019				5,304,989
Series 2 warrants | Private Investment in Public Entities July 2019
Cash flows from financing activities
Proceeds from the issuance of Warrants in Class A and B Units, July 2019				5,304,989
Bridge Note Warrants
Supplemental schedule of non-cash financing and investing activities
Issuance of warrants				5,005,739
Reclassification of warrants from liability to equity	4,259,327			4,259,327
March 2019 LOC warrants
Supplemental schedule of non-cash financing and investing activities
Issuance of warrants				116,297
Reclassification of warrants from liability to equity	71,079			71,079
Series A convertible preferred stock
Supplemental schedule of non-cash financing and investing activities
Deemed dividend					$ 995,000
Series B convertible preferred stock
Supplemental schedule of non-cash financing and investing activities
Deemed dividend	$ 3,875,778			3,875,778
Class A units
Cash flows from financing activities
Payment of underwriting discounts, commissions and other associated offering costs				(875,122)
Class A units | Private Investment in Public Entities July 2019
Cash flows from financing activities
Proceeds from the issuance of common stock				2,074,244
Class B units | Private Investment in Public Entities July 2019
Cash flows from financing activities
Payment of underwriting discounts, commissions and other associated offering costs				$ (1,635,184)