CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
Revenue
Total revenue	$ 972,779	$ 1,132,067	$ 4,268,206	$ 2,820,269
Operating expenses
Cost of product revenue	947,495	736,733	3,072,800	1,808,918
Research and development	1,307,296	1,481,166	4,426,308	3,843,918
Sales and marketing	1,698,440	2,716,752	5,436,635	7,119,204
General and administrative	3,106,633	2,703,628	9,816,909	8,761,776
Settlement of Tempesta Royalty License Agreement	640,000		640,000
Impairment of indefinite-lived intangible assets	0	0	4,000,000	0
Total operating expenses	7,699,864	7,638,279	27,392,652	21,533,816
Loss from operations	(6,727,085)	(6,506,212)	(23,124,446)	(18,713,547)
Interest expense	(1,352,845)	(872,044)	(5,556,953)	(2,185,868)
Other income (expense)	28,784	9,540	49,392	322,244
Change in fair value of warrants, derivative liability and conversion option liability	841,834	26,231	1,002,865	(119,134)
Gain on Valeant settlement		1,204,133		1,204,133
Loss on extinguishment of debt	(335,753)		(4,940,911)
Loss before income tax	(7,545,065)	(6,138,352)	(32,570,053)	(19,492,172)
Income tax expense	(10,000)		(10,000)
Net loss and comprehensive loss	(7,555,065)	(6,138,352)	(32,580,053)	(19,492,172)
Net loss attributable to common shareholders	$ (11,682,949)	$ (6,138,352)	$ (36,707,937)	$ (20,487,172)
Net loss per share, basic and diluted (in dollars per share)	$ (2.00)	$ (37.77)	$ (13.37)	$ (143.25)
Weighted-average common shares outstanding, basic and diluted (in shares)	5,841,790	162,506	2,746,523	143,012
Series A convertible preferred stock
Operating expenses
Deemed dividend				$ (995,000)
Series B convertible preferred stock
Operating expenses
Deemed dividend	$ (3,875,778)		$ (3,875,778)
Series 1 warrants
Operating expenses
Deemed dividend	(252,106)		(252,106)
Product revenue, net
Revenue
Total revenue	$ 972,779	$ 1,132,067	$ 4,268,206	2,642,880
Collaboration revenue
Revenue
Total revenue				$ 177,389