Stock Incentive Plans (Tables)

9 Months Ended

Sep. 30, 2019

Stock Based Compensation

Summary of incentive plan activity

				Weighted		Weighted Average
	Shares	Stock		Average		Remaining	Aggregate
	Available	Options	RSUs	Stock Option		Contractual Life	Intrinsic
	for Grant	Outstanding	Outstanding	Exercise Price		(Years)	Value*
Outstanding at December 31, 2018	2,327	42,979	5,613	$	406.36	9.24	$	—
Additional shares authorized	4,330,400	—	—		—	—
Options granted	(4,306,832)	4,306,832	—		1.71	—		—
Options cancelled	528,121	(528,121)	—		4.45	—		—
Outstanding at September 30, 2019	554,016	3,821,690	5,613	$	5.72	9.81	$	—
Exercisable at September 30, 2019		503,943		$	24.61	9.76	$	—
Vested and expected to vest at September 30, 2019		3,197,953		$	6.82	9.81	$	—

*Fair market value of JAGX common stock on September 30, 2019 was $1.31 per share.

Summary of stock-based compensation expense

	Three Months Ended				Nine Months Ended
	September 30,				September 30,
	2019		2018		2019		2018
	(unaudited)				(unaudited)
Research and development expense	$	332,636	$	175,772	$	548,524	$	400,521
Sales and marketing expense		41,122		39,210		87,215		59,762
General and administrative expense		736,351		465,112		1,347,246		956,508
Total	$	1,110,109	$	680,094	$	1,982,985	$	1,416,791

Employee stock options

Stock Based Compensation

Schedule of estimated grant-date fair value of stock options calculated using the Black-Scholes option-pricing model

	Nine Months Ended
	September 30,
	2019		2018
	(unaudited)
Weighted-average volatility	142.9 -  145.9	%	95.6 - 95.9	%
Weighted-average expected term (years)	5.6 - 5.8		5.8
Risk-free interest rate	1.5 - 1.9	%	2.8 - 3.1	%
Expected dividend yield	—		—