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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Revenue        
Total revenue $ 1,705,694 $ 883,846 $ 3,295,427 $ 1,688,202
Operating expenses        
Cost of product revenue 1,260,362 608,024 2,125,305 1,072,185
Research and development 1,697,653 1,604,886 3,119,013 2,362,752
Sales and marketing 2,173,071 2,690,262 3,738,195 4,402,452
General and administrative 3,196,861 3,059,748 6,710,275 6,058,148
Impairment of indefinite-lived intangible assets 4,000,000 0 4,000,000 0
Total operating expenses 12,327,947 7,962,920 19,692,788 13,895,537
Loss from operations (10,622,253) (7,079,074) (16,397,361) (12,207,335)
Interest expense (3,656,978) (711,802) (4,204,108) (1,313,824)
Other income, net 14,224 15,204 20,608 312,704
Change in fair value of warrants, derivative liability and conversion option liability 207,088 118,489 161,031 (145,365)
Loss on extinguishment of debt (2,663,198)   (4,605,158)  
Net loss (16,721,117) (7,657,183) (25,024,988) (13,353,820)
Deemed dividend attributable to preferred stock   (995,000)   (995,000)
Net loss attributable to common shareholders $ (16,721,117) $ (8,652,183) $ (25,024,988) $ (14,348,820)
Net loss per share, basic and diluted (in dollars per share) $ (15.11) $ (53.24) $ (31.22) $ (100.33)
Weighted-average common shares outstanding, basic and diluted (in shares) 1,106,374 162,506 801,482 143,012
Product revenue, net        
Revenue        
Total revenue $ 1,705,694 $ 883,846 $ 3,295,427 $ 1,510,813
Collaboration revenue        
Revenue        
Total revenue       $ 177,389