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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Revenue    
Total revenue $ 1,589,733 $ 804,356
Operating expenses    
Cost of product revenue 864,943 464,161
Research and development 1,421,360 757,866
Sales and marketing 1,565,124 1,712,190
General and administrative 3,513,414 2,998,400
Total operating expenses 7,364,841 5,932,617
Loss from operations (5,775,108) (5,128,261)
Interest expense (547,130) (602,022)
Other income, net 6,384 297,500
Change in fair value of warrants, derivative liability and conversion option liability (46,057) (263,854)
Loss on extinguishment of debt (1,941,960)  
Net loss (8,303,871) (5,696,637)
Deemed dividend attributable to preferred stock   995,000
Net loss attributable to common shareholders $ (8,303,871) $ (6,691,637)
Net loss per share, basic and diluted (in dollars per share) $ (0.24) $ (0.75)
Weighted-average common shares outstanding, basic and diluted (in shares) 34,524,145 8,631,142
Product revenue, net    
Revenue    
Total revenue $ 1,589,733 $ 626,967
Collaboration revenue    
Revenue    
Total revenue   $ 177,389