Debt and Warrants - Warrants (Details)		1 Months Ended				5 Months Ended	7 Months Ended	12 Months Ended
	Sep. 11, 2018 shares	Oct. 31, 2018 Y $ / shares shares	Aug. 31, 2018 USD ($) Y $ / shares shares	Jul. 31, 2017 $ / shares shares	Nov. 30, 2016 USD ($) Y $ / shares shares	Dec. 31, 2018 USD ($) Y $ / shares shares	Jul. 31, 2018 shares	Dec. 31, 2018 USD ($) Y $ / shares shares	Dec. 31, 2017 USD ($) Y shares
Warrant Activity
Number of warrants issued to purchase shares of common stock (in shares)						759,396		759,396	1,036,717
Warrant liability | $						$ 220,376		$ 220,376	$ 103,860
Warrants granted								2,166,588	106,376
Warrants exercised									60,553
Warrants expired								60,249	122,413
Change in warrant liability | $								$ (331,016)	$ (695,341)
Series A warrants and placement agent warrants | Expected life
Warrant Activity
Warrants - Measurement input | Y					5.5
Series A warrants and placement agent warrants | Volatility
Warrant Activity
Warrants - Measurement input					71.92
Series A warrants and placement agent warrants | Risk free rate
Warrant Activity
Warrants - Measurement input					1.87
Series A Warrants
Convertible Promissory Notes and Common Stock Warrants [Line Items]
Shares issued (in shares)					111,111
Warrant Activity
Number of warrants issued to purchase shares of common stock (in shares)					111,111
Change in fair value of derivative liability | $								96,472
Warrant liability | $					$ 756,001	$ 7,388		$ 7,388	$ 103,860
Series A Warrants | Strike price
Warrant Activity
Warrants - Measurement input					11.25	11.25		11.25	11.25
Series A Warrants | Stock price
Warrant Activity
Warrants - Measurement input						0.23		0.23	0.14
Series A Warrants | Expected life
Warrant Activity
Warrants - Measurement input | Y						3.41		3.41	4.41
Series A Warrants | Volatility
Warrant Activity
Warrants - Measurement input						135.63		135.63	96.36
Series A Warrants | Risk free rate
Warrant Activity
Warrants - Measurement input						2.46		2.46	2.14
Placement agent Warrants
Warrant Activity
Number of warrants issued to purchase shares of common stock (in shares)					8,889
Placement agent Warrants | Strike price
Warrant Activity
Warrants - Measurement input | $ / shares					11.25
Series B warrants
Warrant Activity
Number of warrants issued to purchase shares of common stock (in shares)					111,111
Series C warrants
Warrant Activity
Number of warrants issued to purchase shares of common stock (in shares)					111,111
Financing Warrants
Warrant Activity
Number of warrants issued to purchase shares of common stock (in shares)			30,000
Term			5 years
Warrants expired			17,582
Financing Warrants | Strike price
Warrant Activity
Warrants - Measurement input | $ / shares			1.06
Financing Warrants | Stock price
Warrant Activity
Warrants - Measurement input | $ / shares			1.06
Financing Warrants | Expected life
Warrant Activity
Warrants - Measurement input | Y			5
Financing Warrants | Volatility
Warrant Activity
Warrants - Measurement input			126
Financing Warrants | Risk free rate
Warrant Activity
Warrants - Measurement input			3.83
Underwriter Warrants
Warrant Activity
Exercise price (in dollars per share) | $ / shares		$ 0.75
Warrant liability | $						$ 212,988		$ 212,988
Warrants granted		1,200,000
Warrants expired		611,286
Change in warrant liability | $								$ 398,298
Underwriter Warrants | Strike price
Warrant Activity
Warrants - Measurement input		0.75				0.75		0.75
Underwriter Warrants | Stock price
Warrant Activity
Warrants - Measurement input		0.59				0.23		0.23
Underwriter Warrants | Expected life
Warrant Activity
Warrants - Measurement input | Y		5				4.76		4.76
Underwriter Warrants | Volatility
Warrant Activity
Warrants - Measurement input		137.87				135.63		135.63
Underwriter Warrants | Risk free rate
Warrant Activity
Warrants - Measurement input		2.51				2.51		2.51
License Transaction Warrants Member
Warrant Activity
Warrants exercised						33,333	66,667
Warrants expired			6,312
License Transaction Warrants Member | Strike price
Warrant Activity
Warrants - Measurement input | $ / shares			1.06
License Transaction Warrants Member | Stock price
Warrant Activity
Warrants - Measurement input | $ / shares			1.06
License Transaction Warrants Member | Expected life
Warrant Activity
Warrants - Measurement input | Y			5
License Transaction Warrants Member | Volatility
Warrant Activity
Warrants - Measurement input			126
License Transaction Warrants Member | Risk free rate
Warrant Activity
Warrants - Measurement input			3.83
Minimum | Financing Warrants
Convertible Promissory Notes and Common Stock Warrants [Line Items]
Amount of shares issued | $			$ 3,000,000
Common Stock
Convertible Promissory Notes and Common Stock Warrants [Line Items]
Shares issued (in shares)	75,000
Share issue price (in dollars per share) | $ / shares						$ 0.23		$ 0.23
Napo
Warrant Activity
Fair value of warrants | $						$ 630,859		$ 630,859
Warrants granted				81,649
Napo | Strike price
Warrant Activity
Warrants - Measurement input | $ / shares						0.08		0.08
Napo | Stock price
Warrant Activity
Warrants - Measurement input | $ / shares						0.56		0.56
Napo | Warrants Expired, December 31, 2018
Warrant Activity
Warrants expired								9,696
Napo | Warrants Expired, December 31, 2025
Warrant Activity
Warrants expired								71,953
Napo | Minimum | Expected life
Warrant Activity
Warrants - Measurement input | Y						1.42		1.42
Napo | Minimum | Volatility
Warrant Activity
Warrants - Measurement input						75.07		75.07
Napo | Minimum | Risk free rate
Warrant Activity
Warrants - Measurement input						1.28		1.28
Napo | Maximum | Expected life
Warrant Activity
Warrants - Measurement input | Y						8.42		8.42
Napo | Maximum | Volatility
Warrant Activity
Warrants - Measurement input						110.03		110.03
Napo | Maximum | Risk free rate
Warrant Activity
Warrants - Measurement input						2.14		2.14
Napo | Common Stock
Warrant Activity
Exercise price (in dollars per share) | $ / shares				$ 1.20
Private Placement
Warrant Activity
Exercise price (in dollars per share) | $ / shares					$ 11.25