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CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY - USD ($)
Private Investment in Public Entities June 2016
Common Stock
Common stock - voting
Private Investment in Public Entities June 2016
Additional Paid-in Capital
Private Investment in Public Entities June 2016
Private Investment in Public Entities
Common Stock
Common stock - voting
Private Investment in Public Entities
Additional Paid-in Capital
Private Investment in Public Entities
Private Investment in Public Entities June 2017
Common Stock
Common stock - voting
Private Investment in Public Entities June 2017
Additional Paid-in Capital
Private Investment in Public Entities June 2017
Private Investment in Public Entities November 2017
Common Stock
Common stock - voting
Private Investment in Public Entities November 2017
Additional Paid-in Capital
Private Investment in Public Entities November 2017
Private Investment in Public Entities March 2018
Common Stock
Common stock - voting
Private Investment in Public Entities March 2018
Additional Paid-in Capital
Private Investment in Public Entities March 2018
Series A Preferred Stock
Private Investment in Public Entities March 2018
Private Investment in Public Entities July 2018
Common Stock
Common stock - voting
Private Investment in Public Entities July 2018
Additional Paid-in Capital
Private Investment in Public Entities July 2018
Private investment in public entities with new investors
Common Stock
Common stock - voting
Private investment in public entities with new investors
Additional Paid-in Capital
Private investment in public entities with new investors
Private investment in public entities with existing investors
Common Stock
Common stock - voting
Private investment in public entities with existing investors
Additional Paid-in Capital
Private investment in public entities with existing investors
October 2018 Equity Financing
Common Stock
Common stock - voting
October 2018 Equity Financing
Additional Paid-in Capital
October 2018 Equity Financing
September 2018 L2 convertible note payable
Common Stock
Common stock - voting
September 2018 L2 convertible note payable
Additional Paid-in Capital
September 2018 L2 convertible note payable
Office lease extension agreement
Additional Paid-in Capital
Office lease extension agreement
Common Stock
Common stock - voting
Common Stock
Common stock - non-voting
Additional Paid-in Capital
Common stock - voting
Additional Paid-in Capital
Common stock - non-voting
Additional Paid-in Capital
Deficit Accumulated During the Development Stage
Series A Preferred Stock
Common stock - voting
Common stock - non-voting
Total
Balance at Dec. 31, 2016                                                                   $ 93       $ 37,981,829 $ (40,436,108)       $ (2,454,185)
Balance (in shares) at Dec. 31, 2016                                                                   933,809                  
Increase (decrease) in Stockholders' Equity (Deficit)                                                                                      
Issuance of common stock in a private investment in public entities offering, net of offering costs of $72,710 and $6,000 $ 26 $ 2,314,347 $ 2,314,374       $ 1 $ 93,999 $ 94,000                                                                    
Issuance of common stock in a private investment in public entities offering, net of offering costs of $72,710 and $6,000 (in shares) 264,819           13,333                                                                        
Issuance of common stock through a stock purchase agreement with a private investor, net of offering costs of $44,738 November 2017                   $ 34 $ 555,228 $ 555,262                                                              
Issuance of common stock through a stock purchase agreement with a private investor, net of offering costs of $44,738 November 2017 (in shares)                   340,000                                                                  
Issuance of common stock       $ 27 $ 400,973 $ 401,000                                                       $ 22       2,999,978         3,000,000
Issuance of common stock (in shares)       267,333                                                           216,216                  
Issuance of common stock in the merger                                                                   $ 15 $ 4,317 $ 1,278,154 $ 24,172,725       $ 1,278,169 $ 24,177,042  
Issuance of common stock in the merger (in shares)                                                                   152,163 43,173,288                
Issuance of common stock in a follow-on offering registration statement October 2017, net of commissions and offering costs of $763,502                                                                   $ 145       3,573,853         3,573,998
Issuance of common stock in a follow-on offering registration statement October 2017, net of commissions and offering costs of $763,502 (in shares)                                                                   1,445,833                  
Issuance of warrants in the merger                                                                           630,859         630,859
Issuance of stock options in the merger                                                                           5,691         5,691
Issuance of RSUs in the merger                                                                           3,300,555         3,300,555
Issuance of common stock in exchange of warrants                                                                   $ 6       386,328         386,334
Issuance of common stock in exchange of warrants (in shares)                                                                   60,556                  
Warrants, issued in conjunction with debt extinguishment                                                                           207,713         207,713
Issuance of common stock in exchange for vested restricted stock units (in shares)                                                                   914                  
Issuance of common stock in exchange for redemption of convertible debt                                                                   $ 43       900,320         900,363
Issuance of common stock in exchange for redemption of convertible debt (in shares)                                                                   432,806                  
Issuance of common stock in exchange for services                                                                   $ 2       43,827         $ 43,829
Issuance of common stock in exchange for services (in shares)                                                                   15,676                  
Conversion of non-voting common stock to voting common stock                                                                   $ 4 $ (55)     51          
Conversion of non-voting common stock to voting common stock (in shares)                                                                   37,026 (555,395)                
Shares issued from pre-funded warrants (in shares)                                                                                     106,376
Stock-based compensation                                                                           814,613         $ 814,613
Net loss                                                                             (21,968,614)       (21,968,614)
Balance at Dec. 31, 2017                                                                   $ 418 $ 4,262     79,661,044 (62,404,722)       17,261,002
Balance (in shares) at Dec. 31, 2017                                                                   4,180,484 42,617,893                
Increase (decrease) in Stockholders' Equity (Deficit)                                                                                      
Issuance of preferred stock and common stock in a private investment in public entities March 2018                         $ 196 $ 4,999,804 $ 9,000,002 $ 5,000,000                                                      
Issuance of preferred stock and common stock in a private investment in public entities March 2018 (in shares)                         1,960,794   5,524,926                                                        
Beneficial conversion feature of the series A convertible preferred stock March 2018                                                                           995,000   $ (995,000)     995,000
Deemed dividend on Series A convertible preferred stock March 2018                                                                           (995,000)   995,000     (995,000)
Issuance of common stock in a private investment in public entities offering, net of offering costs of $72,710 and $6,000                                 $ 47 $ 624,850 $ 624,897 $ 72 $ 1,305,702 $ 1,305,774 $ 48 $ 750,052 $ 750,100       $ 7 $ 47,993 $ 48,000                        
Issuance of common stock in a private investment in public entities offering, net of offering costs of $72,710 and $6,000 (in shares)                                 470,781     716,425     478,853           75,000                            
Issuance of warrants in the merger                                                     $ 23,894 $ 23,894   $ 118,149 $ 118,149 $ 493,688 $ 493,688                    
Issuance of common stock in exchange for redemption of convertible debt                                                                   $ 96       1,607,325         1,607,421
Issuance of common stock in exchange for redemption of convertible debt (in shares)                                                                   956,553                  
Issuance of common stock in exchange for services                                                                           6,425         6,425
Issuance of common stock in exchange for services (in shares)                                                                   3,333                  
Issuance of common stock in exchange for payment of interest expense July 2018                                                                   $ 29       704,696         704,725
Issuance of common stock in exchange for payment of interest expense (in shares) July 2018                                                                   285,694                  
Conversion of non-voting common stock to voting common stock                                                                   $ 15 $ (232)     217          
Conversion of non-voting common stock to voting common stock (in shares)                                                                   154,443 (2,316,656)                
Issuance of common stock in lieu of interest July 2018                                                                   $ 32       479,776         479,808
Issuance of common stock in lieu of interest (in shares) July 2018                                                                   320,743                  
Fractional common stock shares repurchased                                                                           (30)         $ (30)
Shares issued in S-1 offering, net of issuance costs                                                   $ 1,157 5,025,293 5,026,450                              
Shares issued in S-1 offering, net of issuance costs (in shares)                                                   11,575,001                                  
Shares issued from pre-funded warrants                                                   $ 343 $ 2,054,658 $ 2,055,001                              
Shares issued from pre-funded warrants (in shares)                                                   3,425,000                                 2,166,588
Stock-based compensation                                                                           2,023,874         $ 2,023,874
Net loss                                                                             (32,146,057)       (32,146,057)
Balance at Dec. 31, 2018                                                                   $ 2,460 $ 4,030     $ 99,927,410 $ (94,550,779)       5,383,121
Ending Balance at Dec. 31, 2018                                                                               $ 9,000,002     $ 9,000,002
Balance (in shares) at Dec. 31, 2018                                                                   24,603,104 40,301,237         5,524,926