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Stock Incentive Plans - Summary of Stock Incentive Plans (Details) - USD ($)
9 Months Ended 12 Months Ended
May 12, 2015
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Jun. 29, 2018
Shares Available for Grant          
Ending balance (in shares)   238,172 513,385    
Stock Options Outstanding          
Ending balance (in shares)   2,868,868 2,984,304    
RSUs Outstanding          
Ending balance (in shares)   392,904 392,923    
Options vested, exercisable and expected to vest          
Weighted average grant date fair value of stock options granted (in dollars per share)   $ 1.84 $ 0.44    
Number of options vested (in shares)   423,719 533,348    
Weighted average fair value of options vested on grant date   $ 475,123 $ 549,453    
Inducement options          
Stock Options Outstanding          
Options granted (in shares)   209,531      
Ending balance (in shares)   209,531      
Options vested, exercisable and expected to vest          
Weighted average grant date fair value of stock options granted (in dollars per share)   $ 1.34      
Number of options vested (in shares)   0      
Common Stock          
Options vested, exercisable and expected to vest          
Share Price         $ 0.87
2013 Plan          
Stock Incentive Plans          
Option shares outstanding   33,769      
2013 Plan | Stock options          
Stock Options Outstanding          
Options granted (in shares)   0      
Ending balance (in shares)   33,769      
2014 Plan          
Stock Incentive Plans          
Option shares outstanding   2,835,099      
Shares Available for Grant          
Beginning balance (in shares)   3,619      
Additional shares authorized (in shares)   2,877,766      
Options granted (in shares)   (2,767,673)      
Options cancelled (in shares)   124,460      
Ending balance (in shares)   238,172   3,619  
Stock Options Outstanding          
Beginning balance (in shares)   229,575      
Options granted (in shares)   2,767,673      
Options cancelled (in shares)   (128,380)      
Ending balance (in shares)   2,868,868   229,575  
RSUs Outstanding          
Beginning balance (in shares)   392,904      
Ending balance (in shares)   392,904   392,904  
Weighted Average Stock Option Exercise Price          
Beginning balance (in dollars per share)   $ 28.05      
Ending balance (in dollars per share)   $ 5.96   $ 28.05  
Weighted Average Remaining Contractual Life (Years)          
Weighted Average Remaining Contractual Life (Years)   9 years 3 months 7 days   8 years 3 months 22 days  
Options vested, exercisable and expected to vest          
Options vested and exercisable (in shares)   709,721      
Options vested and exercisable (in dollars per share)   $ 12.14      
Options vested and exercisable (in years)   3 years 11 months 23 days      
Options vested and expected to vest (in shares)   2,644,568      
Options vested and expected to vest (in dollars per share)   $ 6.03      
Options vested and expected to vest (in years)   9 years 3 months 4 days      
Options exercised (in shares)   0 0    
2014 Plan | Stock options          
Stock Incentive Plans          
Increase in share reserve based on outstanding number of shares (as a percent) 2.00%