Stock-based Compensation - Summary of Stock Incentive Plans (Details) - USD ($)				1 Months Ended	9 Months Ended	12 Months Ended
	Aug. 13, 2024	Jun. 16, 2020	May 12, 2015	Nov. 30, 2013	Sep. 30, 2025	Dec. 31, 2024	Dec. 31, 2023
Stock-based Compensation
Option outstanding					28,734	30,469
Options available for grant under stock option plans					337,402	17,695
Shares Available for Grant
Beginning balance (in shares)					17,695
Ending balance (in shares)					337,402	17,695
Stock Options Outstanding
Beginning balance (in shares)					30,469
Ending balance (in shares)					28,734	30,469
RSUs Outstanding
Beginning balance (in shares)					220
Ending balance (in shares)					8,408	220
Options vested, exercisable and expected to vest
Weighted average grant date fair value of stock options granted (in dollars per share)					$ 4.39	$ 30.33
Number of options vested (in shares)					6,493	1,437
Weighted average fair value of options vested on grant date					$ 29.75	$ 142.01
Stock options
Stock Options Outstanding
Options exercised (in shares)					0	0
Weighted Average Stock Option Exercise Price
Beginning balance (in dollars per share)					$ 311	$ 893,466
Options granted (in dollars per share)					5	32
Options cancelled (in dollars per share)					32	221
Ending balance (in dollars per share)					$ 3,409	$ 311	$ 893,466
Weighted Average Remaining Contractual Life (Years)
Weighted Average Remaining Contractual Life (Years)					8 years 11 months 8 days	9 years 9 months 7 days	6 years 2 months 15 days
Options vested, exercisable and expected to vest
Options exercisable (in dollars per share)					$ 425.02
Options exercisable (in years)					8 years 8 months 8 days
Options vested and expected to vest (in dollars per share)					$ 425.02
Options vested and expected to vest (in years)					8 years 8 months 8 days
Options exercised (in shares)					0	0
Stock options and RSUs
Stock-based Compensation
Option outstanding					29,602	30,470	16
Options available for grant under stock option plans					337,402	17,695	417
Shares Available for Grant
Beginning balance (in shares)					17,695	417
Additional shares authorized (in shares)					327,027	46,154
Options granted (in shares)					(520)	(30,578)
Options cancelled (in shares)					1,388	124
RSUs granted (in shares)					(12,100)	(5,644)
RSUs vested (in shares)					(1,292)
RSUs cancelled					5,204	6
RSUs vested and released (in shares)						7,216
Ending balance (in shares)					337,402	17,695	417
Stock Options Outstanding
Beginning balance (in shares)					30,470	16
Options granted (in shares)					520	30,578
Options cancelled (in shares)					(1,388)	(124)
Ending balance (in shares)					29,602	30,470	16
RSUs Outstanding
RSUs vested and released (in shares)						(7,216)
Options vested, exercisable and expected to vest
Options exercisable (in shares)					7,869
Options vested and expected to vest (in shares)					7,869
Restricted stock units issued and outstanding
Shares Available for Grant
RSUs vested and released (in shares)						7,216
RSUs Outstanding
Beginning balance (in shares)					220	1,798
RSUs Granted (in shares)					12,100	5,644
RSUs Vested (in shares)					1,292
RSUs vested and released (in shares)						(7,216)
RSUs Cancelled (in shares)					(5,204)	(6)
Ending balance (in shares)					8,408	220	1,798
2013 Plan
Stock-based Compensation
Option shares outstanding					0	0
2013 Plan | Stock options
Stock Options Outstanding
Options granted (in shares)				0
2014 Plan
Stock-based Compensation
Incentive stock option term			10 years
Increase in share reserve based on outstanding number of shares (as a percent)			5.00%
Option outstanding					29,081	30,469
Options available for grant under stock option plans					335,672	149
Shares Available for Grant
Beginning balance (in shares)					149
Ending balance (in shares)					335,672	149
Stock Options Outstanding
Beginning balance (in shares)					30,469
Ending balance (in shares)					29,081	30,469
2020 Inducement Award Plan
Stock-based Compensation
Options available for grant under stock option plans		2,222
Number of shares reserved for issuance	58,540
Shares Available for Grant
Ending balance (in shares)		2,222
2020 New Employee Inducement Award Plan
Stock-based Compensation
Incentive stock option term		10 years
Option outstanding					521	1
Options available for grant under stock option plans					1,730	17,546
Number of shares reserved for issuance	78,561
Shares Available for Grant
Beginning balance (in shares)					17,546
Additional shares authorized (in shares)	19,721
Ending balance (in shares)					1,730	17,546
Stock Options Outstanding
Beginning balance (in shares)					1
Ending balance (in shares)					521	1
Common Stock
Options vested, exercisable and expected to vest
Share Price					$ 2.33
Participants Voting Power More than Ten Percent | 2014 Plan
Stock-based Compensation
Incentive stock option term			5 years
Participants Voting Power More than Ten Percent | 2020 Inducement Award Plan
Stock-based Compensation
Incentive stock option term		five years