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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Cash Flows from Operating Activities    
Net loss $ (11,057,169) $ (12,160,729)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 32,463  
Gain/loss on disposal of fixed assets   34,549
Materials cost in connection with license activity   6,287
Stock-based compensation 478,442 828,049
Amortization of debt issuance costs and debt discount 396,107 2,592,956
Change in fair value of warrants   501,617
Changes in assets and liabilities    
Accounts receivable - trade 50,904 (8,698)
Inventory (46,356) (58,100)
Prepaid expenses (331,124) (329,774)
Deferred finance charges   (197,524)
Other long-term assets   (122,163)
Due from parent (269,863) (20,790)
Deferred revenue (5,701) 312,910
Deferred rent 3,478 1,660
License fee payable (425,000) (675,000)
Accounts payable (151,912) (421,551)
Accrued expenses (360,776) (669,634)
Total cash used in operations (11,686,507) (10,385,935)
Cash Flows from Investing Activities    
Purchase of equipment (104,207) (23,300)
Sale of equipment   20,600
Change in restricted cash 2,011,420 (4,500,000)
Total cash provided by (used in) investing activities 1,907,213 (4,502,700)
Cash Flows from Financing Activities    
Proceeds from issuance of long-term debt   5,865,567
Repayment of long-term debt (2,011,420)  
Proceeds from issuance of redeemable convertible notes payable, net   1,250,000
Repayment of convertible notes payable   (100,000)
Repayment of notes payable   (1,000,000)
Proceeds from issuance of common stock in initial public offering, net of commissions and discounts   18,810,484
Deferred offering costs   (417,775)
Proceeds from issuance of common stock in a follow-on secondary offering, net of commissions and discounts 4,130,102  
Proceeds from issuance of common stock in a private investment in public entities, net of commissions, discounts 1,776,492  
Proceeds from the exercise of common stock options   12,650
Total Cash Provided by Financing Activities 3,895,174 24,420,926
Net increase in cash and cash equivalents (5,884,120) 9,532,291
Cash and cash equivalents, beginning of period 7,697,531 845,192
Cash and cash equivalents, end of period 1,813,411 10,377,483
Supplemental Schedule of Non-Cash Financing and Investing Activities    
Interest paid on long-term debt $ 382,810 23,100
Offering costs not paid during the nine months   1,401,253
Accretion of redeemable convertible preferred stock   346,374
Abatement of license fee payable to Napo   250,000
Conversion of convertible preferred stock to common stock   7,651,288
Conversion of preferred stock warrant liability to common stock warrants   1,150,985
Conversion of convertible notes to common stock   $ 2,100,000