Balance Sheet Components (Tables)

3 Months Ended

12 Months Ended

Mar. 31, 2017

Dec. 31, 2016

Balance Sheet Components

Schedule of property and equipment

	March 31,			December 31,
	2017			2016
Lab equipment	$	811,087		$	811,087
Clinical equipment	64,870			64,870
Software	62,637			62,637
Total property and equipment at cost	938,594			938,594
Accumulated Depreciation	(67,680		)	(52,649		)
Property and Equipment, net	$	870,914		$	885,945

	December 31, 2016			December 31, 2015
Lab equipment	$	811,087		$	811,087
Clinical equipment		64,870			23,300
Software		62,637			—
Total property and equipment at cost		938,594			834,387
Accumulated Depreciation		(52,649	)		(5,155	)
Property and Equipment, net	$	885,945		$	829,232

Schedule of depreciation expense

	Three Months Ended
	March 31,
	2017		2016
Depreciation - Lab Equipment - research and development expense	$	6,568	$	6,568
Depreciation - Clinical Equipment - research and development expense	3,243		1,165
Depreciation - Software - general and administrative expense	5,220		145
Total Depreciation Expense	$	15,031	$	7,878

	Years Ended December 31,
	2016		2015
Depreciation—Lab Equipment—research and developoment expense	$	26,271	$	4,378
Depreciation—Clinical Equipment—research and development expense		10,203		777
Depreciation—Software—general and administrative expense		11,020		—
Total Depreciation Expense	$	47,494	$	5,155

Schedule of accrued expenses

	March 31,		December 31,
	2017		2016
Accrued compensation and related:
Accrued vacation	$	229,944	$	223,769
Accrued payroll	—		2,692
Accrued payroll tax	21,843		20,140
	251,787		246,601
Accrued interest	124,242		123,982
Accrued clinical	—		36,725
Accrued legal costs	855,397		92,500
Accrued audit	20,000		37,000
Accrued other	14,921		45,714
Total	$	1,266,347	$	582,522

	December 31, 2016		December 31, 2015
Accrued compensation and related:
Accrued vacation	$	223,769		187,734
Accrued payroll		2,692		80,692
Accrued payroll tax		20,140		43,702
		246,601		312,128
Accrued interest		123,982		127,149
Accrued contract manufacturing costs		—		110,141
Accrued clinical		36,725		166,750
Accrued other		175,214		82,266
Total	$	582,522		798,434