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Related Party Transactions - Royalty payable to former parent and license fee payable to former parent and related agreement (Details) - USD ($)
1 Months Ended 12 Months Ended
Jan. 31, 2015
Jan. 31, 2014
Jul. 31, 2013
Dec. 31, 2016
Dec. 31, 2015
License agreement          
Property and equipment, net       $ 885,945 $ 829,232
Option Agreement | Napo          
License agreement          
License fees paid     $ 100,000    
Term of agreement     2 years    
License Agreement | Napo          
License agreement          
License fees paid       425,000 1,200,000
Payment obligation of one-time non-refundable license fee $ 1,750,000 $ 2,000,000      
Option fee   100,000      
Milestone payments due   $ 3,150,000      
Royalty expiration term from the first sale of each individual product   10 years      
Minimum proceeds from IPO prior to December 31, 2015, required for royalty reduction   $ 10,000,000      
Milestone payments due in the event of minimum proceeds from IPO   $ 0      
Unpaid royalties       171  
License Agreement | Napo | Products derived from Croton Lechleri          
License agreement          
Royalty rate for net sales below revenue base (as a percent)   8.00%      
Net product sales upon which royalty rate increases   $ 30,000,000      
Royalty rate for net sales above revenue base (as a percent)   10.00%      
Royalties payments due in the event of minimum proceeds from IPO   $ 0      
License Agreement | Napo | Prescription products derived from Croton Lechleri          
License agreement          
Royalty rate in the event of an IPO in excess of a specified amount   2.00%      
License Agreement | Napo | Nonprescription products derived from Croton Lechleri          
License agreement          
Royalty rate in the event of an IPO in excess of a specified amount   1.00%      
License Agreement | Napo | Pharmaceutical prescription products not derived from Croton Lechleri          
License agreement          
Royalty on annual net sales of products (as a percent)   2.00%      
License Agreement | Napo | Nonprescription products not derived from Croton Lechleri          
License agreement          
Royalty on annual net sales of products (as a percent)   1.00%      
License Agreement | Napo | Accrued Liabilities          
License agreement          
Unpaid royalties         2,810
License Agreement | Napo | Property and equipment          
License agreement          
Property and equipment, net       811,087  
License Agreement | Napo | General and administrative expense          
License agreement          
Royalties incurred       1,015 $ 39,734
License Agreement | Napo | Research and development expense          
License agreement          
Property and equipment, net       $ 1,200,000