Income Taxes (Details) - USD ($)	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014
Income Taxes
Net loss and comprehensive loss	$ 16,291,550	$ 8,609,575
Deferred:
Federal	(4,197,007)	(2,844,539)
State	(587,696)	(511,406)
Total deferred	(4,784,703)	(3,355,945)
Less: valuation allowance	$ 4,784,703	$ 3,355,945
Effective tax rate, differed from the federal statutory rate
Statutory rate (as a percent)	(34.00%)	(34.00%)
State taxes (as a percent)	(3.60%)	(5.90%)
Tax credits (as a percent)	5.20%	(0.80%)
Other (as a percent)	1.70%	2.20%
Valuation allowance (as a percent)	30.70%	38.50%
Effective tax rate (as a percent)	0.00%	0.00%
Non-current deferred tax assets:
Net operating losses	$ 7,459,489	$ 3,610,478
Tax credits	261,851	124,025
Other	(734,611)	56,713
Gross non-current deferred tax assets	8,455,951	3,677,790
Valuation allowance	(8,455,951)	$ (3,677,790)
Increase in valuation allowance	$ 4,784,703