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The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation.

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License Agreement (Details) - USD ($)		1 Months Ended			12 Months Ended
License Agreement (Details) - USD ($)	Mar. 31, 2016	Jan. 31, 2015	Jan. 31, 2014	Jul. 31, 2013	Dec. 31, 2015	Dec. 31, 2014
License agreement
Property and equipment, net					$ 829,232	$ 872,523
Option Agreement \| Napo
License agreement
License fees paid				$ 100,000
Term of agreement				2 years
License Agreement \| Napo
License agreement
License fees paid					$ 1,200,000
Payment obligation of one-time non-refundable license fee		$ 1,750,000	$ 2,000,000
Option fee			100,000
Milestone payments due			$ 3,150,000
Royalty expiration term from the first sale of each individual product			10 years
Minimum proceeds from IPO prior to December 31, 2015, required for royalty reduction			$ 10,000,000
Milestone payments due in the event of minimum proceeds from IPO			0
License Agreement \| Napo \| Forecast
License agreement
License fees paid	$ 425,000
License Agreement \| Napo \| Products derived from Croton Lechleri
License agreement
Royalty rate for net sales below revenue base (as a percent)					8.00%
Net product sales upon which royalty rate increases			$ 30,000,000
Royalty rate for net sales above revenue base (as a percent)			10.00%
Royalties payments due in the event of minimum proceeds from IPO			$ 0
License Agreement \| Napo \| Prescription products derived from Croton Lechleri
License agreement
Royalty rate in the event of an IPO in excess of a specified amount			2.00%
License Agreement \| Napo \| Nonprescription products derived from Croton Lechleri
License agreement
Royalty rate in the event of an IPO in excess of a specified amount			1.00%
License Agreement \| Napo \| Pharmaceutical prescription products not derived from Croton Lechleri
License agreement
Royalty on annual net sales of products (as a percent)			2.00%
License Agreement \| Napo \| Nonprescription products not derived from Croton Lechleri
License agreement
Royalty on annual net sales of products (as a percent)			1.00%
License Agreement \| Napo \| Accrued Liabilities
License agreement
Unpaid royalties					$ 2,810
License Agreement \| Napo \| Property and equipment
License agreement
Property and equipment, net					811,087
License Agreement \| Napo \| General and administrative expense
License agreement
Royalties incurred					39,734
License Agreement \| Napo \| Research and development expense
License agreement
Depreciation expense					$ 4,379