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Stock-based Compensation - Summary of Stock Incentive Plans (Details) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Aug. 13, 2024
Jun. 16, 2020
May 12, 2015
Nov. 30, 2013
Mar. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Stock-based Compensation              
Option outstanding         30,469 30,469  
Options available for grant under stock option plans         37,912 17,695  
Shares Available for Grant              
Beginning balance (in shares)         17,695    
Ending balance (in shares)         37,912 17,695  
Stock Options Outstanding              
Beginning balance (in shares)         30,469    
Ending balance (in shares)         30,469 30,469  
RSUs Outstanding              
Beginning balance (in shares)         220    
Ending balance (in shares)         1,420 220  
Options vested, exercisable and expected to vest              
Weighted average grant date fair value of stock options granted (in dollars per share)         $ 0 $ 30.33  
Number of options vested (in shares)         2,151 1,437  
Weighted average fair value of options vested on grant date         $ 30.33 $ 142.01  
Stock options              
Stock Options Outstanding              
Options exercised (in shares)         0 0  
Weighted Average Stock Option Exercise Price              
Beginning balance (in dollars per share)         $ 311 $ 893,466  
Options granted (in dollars per share)           32  
Options cancelled (in dollars per share)           221  
Ending balance (in dollars per share)         $ 3,347 $ 311 $ 893,466
Weighted Average Remaining Contractual Life (Years)              
Weighted Average Remaining Contractual Life (Years)         9 years 6 months 10 days 9 years 9 months 7 days 6 years 2 months 15 days
Options vested, exercisable and expected to vest              
Options exercisable (in dollars per share)         $ 896    
Options exercisable (in years)         9 years 6 months 7 days    
Options vested and expected to vest (in dollars per share)         $ 151    
Options vested and expected to vest (in years)         9 years 6 months 10 days    
Options exercised (in shares)         0 0  
Stock options and RSUs              
Stock-based Compensation              
Option outstanding         30,470 30,470 16
Options available for grant under stock option plans         37,912 17,695 417
Shares Available for Grant              
Beginning balance (in shares)         17,695 417  
Additional shares authorized (in shares)         21,417 46,154  
Options granted (in shares)           (30,578)  
Options cancelled (in shares)           124  
RSUs granted (in shares)         (3,000) (5,644)  
RSUs exercised         (3)    
RSUs cancelled         1,803 6  
RSUs vested and released (in shares)           7,216  
Ending balance (in shares)         37,912 17,695 417
Stock Options Outstanding              
Beginning balance (in shares)         30,470 16  
Options granted (in shares)           30,578  
Options cancelled (in shares)           (124)  
Ending balance (in shares)         30,470 30,470 16
RSUs Outstanding              
RSUs vested and released (in shares)           (7,216)  
Options vested, exercisable and expected to vest              
Options exercisable (in shares)         3,581    
Options vested and expected to vest (in shares)         26,051    
Restricted stock units issued and outstanding              
Shares Available for Grant              
RSUs vested and released (in shares)           (7,216)  
RSUs Outstanding              
Beginning balance (in shares)         220 1,798  
RSUs Granted (in shares)         3,000 5,644  
RSUs Exercised (in shares)         (3)    
RSUs vested and released (in shares)           7,216  
RSUs Cancelled (in shares)         (1,803) (6)  
Ending balance (in shares)         1,420 220 1,798
2013 Plan              
Stock-based Compensation              
Option shares outstanding         0 0  
2013 Plan | Stock options              
Stock Options Outstanding              
Options granted (in shares)       0      
2014 Plan              
Stock-based Compensation              
Incentive stock option term     10 years        
Increase in share reserve based on outstanding number of shares (as a percent)     2.00%        
Option outstanding         30,469 30,469  
Options available for grant under stock option plans         26,565 149  
Shares Available for Grant              
Beginning balance (in shares)         149    
Ending balance (in shares)         26,565 149  
Stock Options Outstanding              
Beginning balance (in shares)         30,469    
Ending balance (in shares)         30,469 30,469  
2020 Inducement Award Plan              
Stock-based Compensation              
Options available for grant under stock option plans   2,222          
Number of shares reserved for issuance 58,540            
Shares Available for Grant              
Ending balance (in shares)   2,222          
2020 New Employee Inducement Award Plan              
Stock-based Compensation              
Incentive stock option term   10 years          
Option outstanding         1 1  
Options available for grant under stock option plans         11,347 17,546  
Number of shares reserved for issuance 78,561            
Shares Available for Grant              
Beginning balance (in shares)         17,546    
Additional shares authorized (in shares) 19,721            
Ending balance (in shares)         11,347 17,546  
Stock Options Outstanding              
Beginning balance (in shares)         1    
Ending balance (in shares)         1 1  
Common Stock              
Options vested, exercisable and expected to vest              
Share Price         $ 4.76    
Participants Voting Power More than Ten Percent | 2014 Plan              
Stock-based Compensation              
Incentive stock option term     5 years        
Participants Voting Power More than Ten Percent | 2020 Inducement Award Plan              
Stock-based Compensation              
Incentive stock option term   5 years