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CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY - USD ($)
Total
Streeterville
Iliad
Redeemable preferred stock
Redeemable preferred stock
Streeterville
Series G convertible preferred stock
Series I convertible preferred stock
Preferred Stock
Series G convertible preferred stock
Preferred Stock
Series I convertible preferred stock
Preferred Stock
Series I convertible preferred stock
Iliad
Common Stock
Common stock - voting
Common Stock
Common stock - voting
Streeterville
Common Stock
Common stock - voting
Irving
Common Stock
Common stock - voting
Iliad
Common Stock
Common stock - non-voting
Additional paid-in capital
Additional paid-in capital
Streeterville
Additional paid-in capital
Irving
Additional paid-in capital
Iliad
Noncontrolling Interest
Accumulated deficit
Accumulated deficit
Streeterville
Accumulated other comprehensive loss
At The Market Offering
At The Market Offering
Common Stock
Common stock - voting
At The Market Offering
Additional paid-in capital
Warrants issued and outstanding
Common Stock
Common stock - voting
Ending Balance, Redeemable preferred stock at Mar. 31, 2024       $ 2,485,000                                              
Ending Balance, Redeemable preferred stock (in shares) at Mar. 31, 2024       99                                              
Beginning Balance at Dec. 31, 2023 $ 4,897,000                             $ 313,862,000       $ (64,000) $ (308,249,000)   $ (652,000)        
Beginning Balance (in shares) at Dec. 31, 2023               122 56   48,942       9                        
Increase (decrease) in Stockholders' Equity (Deficit)                                                      
Issuance of common stock                                               $ 11,340,000   $ 11,340,000  
Issuance of common stock (in shares)                                                 87,263    
Common shares issued from conversion   $ 1,999,000 $ 836,000   $ (2,000,000)                       $ 1,740,000   $ 836,000     $ 259,000          
Common shares issued from conversion (in shares)         (80)     (122)   (56) 2,033 12,221   1,799                         12,557
Common shares issued to third party in exchange of license agreement                               1,150,000                      
Common shares issued to third party in exchange of license agreement (in shares)                     11,111                                
Shares issued in exchange of notes payable and accrued interest   166,000                             166,000                    
Shares issued in exchange of notes payable and accrued interest (in shares)                       1,059   5,333                          
Preferred stock issued in exchange of notes payable and accrued interest         $ 4,485,000                                            
Preferred stock issued in exchange of notes payable and accrued interest (shares)         179                                            
Stock-based compensation 581,000                             581,000                      
Net loss (9,368,000)                                     (142,000) (9,226,000)            
Translation gain (loss) 217,000                                     26,000     191,000        
Ending Balance at Mar. 31, 2024 $ 11,818,000                             329,675,000       (180,000) (317,216,000)   (461,000)        
Ending Balance (in shares) at Mar. 31, 2024                     182,318       9                        
Increase (decrease) in Stockholders' Equity (Deficit)                                                      
Preferred stock value                                                  
Issued 99         0 0                                        
Beginning Balance, Redeemable preferred stock at Dec. 31, 2024 $ 2,485,000     $ 2,485,000                                              
Beginning Balance, Redeemable preferred stock (in shares) at Dec. 31, 2024 99     99                                              
Ending Balance, Redeemable preferred stock at Mar. 31, 2025 $ 2,485,000     $ 2,485,000                                              
Ending Balance, Redeemable preferred stock (in shares) at Mar. 31, 2025 99     99                                              
Beginning Balance at Dec. 31, 2024 $ 6,494,000                             354,234,000       (791,000) (346,482,000)   (467,000)        
Beginning Balance (in shares) at Dec. 31, 2024                     528,440       9                        
Increase (decrease) in Stockholders' Equity (Deficit)                                                      
Issuance of common stock                                               $ 1,756,000   $ 1,756,000  
Issuance of common stock (in shares)                                                 80,007    
Shares issued in exchange of notes payable and accrued interest   $ 315,000 $ 1,210,000                           $ 315,000 $ 1,210,000                  
Shares issued in exchange of notes payable and accrued interest (in shares)                       51,600 14,000                            
Warrants 1,795,000                             1,795,000                      
Issuance costs attributable to warrants (183,000)                             (183,000)                      
Stock-based compensation 301,000                             301,000                      
Net loss (10,596,000)                                     (132,000) (10,464,000)            
Translation gain (loss) (262,000)                                     (29,000)     (233,000)        
Ending Balance at Mar. 31, 2025 $ 830,000                             $ 359,428,000       $ (952,000) $ (356,946,000)   $ (700,000)        
Ending Balance (in shares) at Mar. 31, 2025                     674,047       9                        
Increase (decrease) in Stockholders' Equity (Deficit)                                                      
Preferred stock value                                                  
Issued 99         0 0