Summary of Significant Accounting Policies - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended		12 Months Ended
	Mar. 31, 2021	Mar. 31, 2020	Dec. 31, 2020
Summary Of Significant Accounting Policies [Line Items]
Research and development	$ 60,193	$ 5,714
Change in accounting principle, accounting standards update, early adoption	true
Change in accounting principle, accounting standards update, adoption date	Jan. 01, 2021
Change in accounting principle, accounting standards update, immaterial effect	true
Accounting Standards Update [Extensible List]	tlis:AccountingStandardsUpdate202006Member
High Capacity Production Equipment | Talis One Cartridges | COVID-19
Summary Of Significant Accounting Policies [Line Items]
Research and development	$ 28,600		$ 69,500
IPO | Other Current Assets
Summary Of Significant Accounting Policies [Line Items]
Deferred offering costs			$ 2,400