Commitments and Contingencies - Additional Information (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2022 USD ($) Option	Dec. 31, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jan. 31, 2022 USD ($)	Jan. 31, 2021 USD ($)
Commitments And Contingencies [Line Items]
Operating lease right-of-use-assets	$ 30,920	$ 12,907
Impairment of long-lived assets	$ 3,593	0
Standby Letters of Credit
Commitments And Contingencies [Line Items]
Line of Credit		$ 1,000
Letter of Credit
Commitments And Contingencies [Line Items]
letter of credit facility					$ 800
Cash collateral for line of credit facility				$ 1,000
Chicago, IL | Letter of Credit
Commitments And Contingencies [Line Items]
Cash collateral for line of credit facility					$ 800
Redwood City, CA | Letter of Credit
Commitments And Contingencies [Line Items]
letter of credit facility				$ 1,000
Laboratory and Office Space | Chicago, IL
Commitments And Contingencies [Line Items]
Renewal term					11 years
Annual minimum commitment					$ 1,700
Fixed escalations percentage per annum					2.50%
Laboratory and Office Space | Redwood City, CA
Commitments And Contingencies [Line Items]
Operating lease right-of-use-assets			$ 23,900
Initial term of operating lease	10 years 6 months
Existence of option to extend operating lease	true
Renewal term	5 years
Annual minimum commitment	$ 2,600
Fixed escalations percentage per annum	3.00%
Impairment of long-lived assets	$ 3,600
Number of options to extend Lease term | Option	2
Payment to landlord	$ 4,700