Stock-Based Compensation - Summary of Stock Option Activity (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended	12 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Number of Units Outstanding, Beginning Balance	8,590,411
Number of Units, Granted	256,800
Number of Units, Exercised	(65,862)
Number of Units, Forfeited	697,607
Number of Units, Expired	161,468
Number of Units Outstanding, Ending Balance	7,922,274	8,590,411
Number of Units, Exercisable	2,753,490
Number of Units, Nonvested	5,168,784
Number of Units Outstanding, Weighted Average Strike Price per Unit, Beginning Balance	$ 5.48
Number of Units, Granted, Weighted Average Strike Price per Unit	1.89
Number of Units, Exercised, Weighted Average Strike Price per Unit	1.50
Number of Units, Forfeited, Weighted Average Exercise Price per Unit	6.67
Number of Units, Expired, Weighted Average Exercise Price per Unit	3.43
Number of Units Outstanding, Weighted Average Strike Price per Unit, Ending Balance	5.33	$ 5.48
Number of Units, Exercisable, Weighted Average Strike Price per Unit	5.28
Number of Units, Nonvested, Weighted Average Strike Price per Unit	$ 5.36
Number of Units Outstanding, Weighted Average Remaining Contractual Term (in years)	8 years 7 months 6 days	8 years 9 months 18 days
Number of Units, Exercisable, Weighted Average Remaining Contractual Term (in years)	8 years 4 months 24 days
Number of Units, Nonvested, Weighted Average Remaining Contractual Term (in years)	8 years 9 months 18 days
Number of Units Outstanding, Aggregate Intrinsic Value	$ 0	$ 6,196
Number of Units, Exercisable, Aggregate Intrinsic Value	0
Number of Units, Nonvested, Aggregate Intrinsic Value	$ 0