Commitments and Contingencies - Additional Information (Details)	3 Months Ended
	Mar. 31, 2022 USD ($) Option	Jan. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Jan. 31, 2021 USD ($)
Commitments And Contingencies [Line Items]
Operating lease right-of-use-assets	$ 12,693,000		$ 12,907,000
Operating lease liability	14,154,000
Unconditional purchase obligation	$ 12,200,000
Standby Letters of Credit
Commitments And Contingencies [Line Items]
LineOfCredit			$ 1,000.0
Letter of Credit
Commitments And Contingencies [Line Items]
Cash collateral for line of credit facility		$ 1,000,000.0
Redwood City, CA | Letter of Credit
Commitments And Contingencies [Line Items]
letter of credit facility		$ 1,000,000.0
Laboratory and Office Space | Chicago, IL
Commitments And Contingencies [Line Items]
Renewal term				11 years
Annual minimum commitment				$ 1,700
Fixed escalations percentage per annum				2.50%
Laboratory and Office Space | Redwood City, CA
Commitments And Contingencies [Line Items]
Initial term of operating lease	10 years 6 months
Existence of option to extend operating lease	true
Renewal term	5 years
Annual minimum commitment	$ 2,600,000
Fixed escalations percentage per annum	3.00%
Number of options to extend Lease term | Option	2