X0202 SCHEDULE 13G/A 0001172661-26-001034 0001583977 XXXXXXXX LIVE 4 Common Stock, $0.001 par value per share 03/31/2026 0002012593 Rapport Therapeutics, Inc. 75383L102 99 High Street Suite 2100 Boston MA 02110 Rule 13d-1(b) Cormorant Asset Management, LP b DE 0.00 2957521.00 0.00 2957521.00 2957521.00 N 6.19 IA PN Bihua Chen b X1 0.00 2957521.00 0.00 2957521.00 2957521.00 N 6.19 HC IN Rapport Therapeutics, Inc. 99 High Street, Suite 2100, Boston, Massachusetts 02110 Cormorant Asset Management, LP Bihua Chen This statement is filed by (i) Cormorant Asset Management, LP, a Delaware limited partnership, and the investment adviser to certain funds (the "Cormorant Funds"), with respect to the shares directly held by the Cormorant Funds and (ii) Bihua Chen with respect to the shares directly held by the Cormorant Funds. The foregoing persons are hereinafter sometimes collectively referred to as the "Reporting Persons." The filing of this statement should not be construed as an admission that any of the foregoing persons or any Reporting Person is, for the purposes of Section 13 of the Act, the beneficial owner of the shares reported herein. 200 Clarendon Street, 52nd Floor Boston, MA 02116 Cormorant Asset Management, LP - Delaware Bihua Chen - United States N IA HC 2,957,521 6.19% 0 2,957,521 0 2,957,521 The percentages reported herein with respect to the Reporting Persons' holdings are calculated based upon a statement in the Issuer's Annual Report on Form 10-K for the fiscal year ended December 31, 2025, as filed with the Securities and Exchange Commission on March 10, 2026, that there were 47,792,943 shares of Common Stock of the Issuer outstanding as of March 2, 2026. Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Joint Filing Statement, incorporated by reference to the Joint Filing Statement included with the Schedule 13G filed by the Reporting Persons on June 20, 2024. Cormorant Asset Management, LP /s/ Bihua Chen 05/15/2026 Bihua Chen /s/ Bihua Chen 05/15/2026