SCHEDULE 13D

CUSIP No.

09077A106

Name of reporting person

Cormorant Global Healthcare Master Fund, LP

Check the appropriate box if a member of a Group (See Instructions)

(a)

(b)

SEC use only

Source of funds (See Instructions)

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

Checkbox not checked

Citizenship or place of organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 1,795,928.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 1,795,928.00

Aggregate amount beneficially owned by each reporting person

1,795,928.00

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in Row (11)

3.15 %

Type of Reporting Person (See Instructions)

SCHEDULE 13D

CUSIP No.

09077A106

Name of reporting person

Cormorant Global Healthcare GP, LLC

Check the appropriate box if a member of a Group (See Instructions)

(a)

(b)

SEC use only

Source of funds (See Instructions)

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

Checkbox not checked

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 1,795,928.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 1,795,928.00

Aggregate amount beneficially owned by each reporting person

1,795,928.00

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in Row (11)

3.15 %

Type of Reporting Person (See Instructions)

SCHEDULE 13D

CUSIP No.

09077A106

Name of reporting person

Cormorant Private Healthcare Fund III LP

Check the appropriate box if a member of a Group (See Instructions)

(a)

(b)

SEC use only

Source of funds (See Instructions)

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

Checkbox not checked

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 1,717,232.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 1,717,232.00

Aggregate amount beneficially owned by each reporting person

1,717,232.00

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in Row (11)

3.01 %

Type of Reporting Person (See Instructions)

SCHEDULE 13D

CUSIP No.

09077A106

Name of reporting person

Cormorant Private Healthcare GP III, LLC

Check the appropriate box if a member of a Group (See Instructions)

(a)

(b)

SEC use only

Source of funds (See Instructions)

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

Checkbox not checked

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 1,717,232.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 1,717,232.00

Aggregate amount beneficially owned by each reporting person

1,717,232.00

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in Row (11)

3.01 %

Type of Reporting Person (See Instructions)

SCHEDULE 13D

CUSIP No.

09077A106

Name of reporting person

Cormorant Asset Management, LP

Check the appropriate box if a member of a Group (See Instructions)

(a)

(b)

SEC use only

Source of funds (See Instructions)

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

Checkbox not checked

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 3,570,872.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 3,570,872.00

Aggregate amount beneficially owned by each reporting person

3,570,872.00

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in Row (11)

6.26 %

Type of Reporting Person (See Instructions)

SCHEDULE 13D

CUSIP No.

09077A106

Name of reporting person

Chen Bihua

Check the appropriate box if a member of a Group (See Instructions)

(a)

(b)

SEC use only

Source of funds (See Instructions)

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

Checkbox not checked

Citizenship or place of organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 110,792.00
8	Shared Voting Power 3,570,872.00
9	Sole Dispositive Power 110,792.00
10	Shared Dispositive Power 3,570,872.00

Aggregate amount beneficially owned by each reporting person

3,681,664.00

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in Row (11)

6.46 %

Type of Reporting Person (See Instructions)

SCHEDULE 13D

Item 1.

Security and Issuer

(a)

Title of Class of Securities:

Common Stock

(b)

Name of Issuer:

Biomea Fusion, Inc.

(c)

Address of Issuer's Principal Executive Offices:

900 MIDDLEFIELD ROAD, 4TH FLOOR, REDWOOD CITY, CALIFORNIA , 94063.

Item 1 Comment:

This Amendment No. 2 to Schedule 13D (this "Amendment") relates to Common Stock of Biomea Fusion, Inc., a Delaware corporation (the "Issuer" or the "Company"). The address of the principal executive offices of the Issuer is 900 Middlefield Road, 4th Floor, Redwood City, California 94063. This Amendment is being filed by the Reporting Persons to amend the Schedule 13D that was filed on April 30, 2021 and amended on April 3, 2023 (as amended, the "Schedule 13D"). Unless otherwise indicated, all capitalized terms used herein but not defined herein shall have the same meaning as in the Schedule 13D.

Item 2.

Identity and Background

(a)

Cormorant Global Healthcare Master Fund, LP Cormorant Global Healthcare GP, LLC Cormorant Private Healthcare Fund III, LP Cormorant Private Healthcare GP III, LLC Cormorant Asset Management, LP Bihua Chen

(b)

200 Clarendon Street, 52nd Floor Boston, MA 02116

(f)

Cormorant Global Healthcare Master Fund, LP - Cayman Islands Cormorant Global Healthcare GP, LLC - Delaware Cormorant Private Healthcare Fund III, LP - Delaware Cormorant Private Healthcare GP III, LLC - Delaware Cormorant Asset Management, LP - Delaware Bihua Chen - United States

Item 5.

Interest in Securities of the Issuer

(a)

See Items 7-13 of the cover page and Item 2.

(b)

See Items 7-13 of the cover page and Item 2. The percentages reported herein with respect to the Reporting Persons' holdings are calculated based upon (i) a statement in a Prospectus filed by the Issuer on June 18, 2025 that there would be 57,022,250 shares of Common Stock outstanding following the closing of a public offering described therein, and (ii) a statement in a Current Report on Form 8-K filed by the Issuer on June 20, 2025 announcing that the public offering closed on that date. The shares reported for Bihua Chen reflect shares of Common Stock that she has the right to receive within 60 days upon the exercise of stock options granted to her in her capacity as a director of the Issuer.

(c)

The Reporting Persons did not engage in any transactions in securities of the Issuer during the sixty day period prior to the filing of this Schedule 13D.

(d)

Not applicable.

(e)

Not applicable.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Cormorant Global Healthcare Master Fund, LP

Signature:	/s/ CORMORANT GLOBAL HEALTHCARE MASTER FUND, LP By: Cormorant Global Healthcare GP, LLC, its General Partner
Name/Title:	By: Bihua Chen, Managing Member
Date:	07/22/2025

Cormorant Global Healthcare GP, LLC

Signature:	/s/ Bihua Chen
Name/Title:	By: Bihua Chen, Managing Member
Date:	07/22/2025

Cormorant Private Healthcare Fund III LP

Signature:	/s/ CORMORANT PRIVATE HEALTHCARE FUND III, LP By: Cormorant Private Healthcare GP III, LLC, its General Partner
Name/Title:	By: Bihua Chen, Managing Member
Date:	07/22/2025

Cormorant Private Healthcare GP III, LLC

Signature:	/s/ Bihua Chen
Name/Title:	By: Bihua Chen, Managing Member
Date:	07/22/2025

Cormorant Asset Management, LP

Signature:	/s/ CORMORANT ASSET MANAGEMENT, LP By: Cormorant Asset Management GP, LLC, its General Partner
Name/Title:	By: Bihua Chen, Managing Member
Date:	07/22/2025

Chen Bihua

Signature:	/s/ Bihua Chen
Name/Title:	Bihua Chen
Date:	07/22/2025