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Income Taxes - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Operating Loss Carryforwards [Line Items]      
Loss before income taxes $ 32,722,168 $ 20,323,354  
Income tax benefit (expense) 0 (30,584)  
Net deferred tax liability (409,022) (409,022) $ (409,022)
Increase (Decrease) in valuation allowance 8,800,000 2,500,000  
Net operating loss carryforwards 101,100,000 $ 49,600,000 $ 56,800,000
Tax credit carry forwards 1,200,000    
Unrecognized tax benefits 0    
Unrecognized tax benefits, interest and penalties accrued 0    
Unrecognized tax benefits that would impact to the effective rate if recognized 0    
Undistributed earnings 900,000    
Ciclofilin      
Operating Loss Carryforwards [Line Items]      
Net deferred tax liability $ (409,022)