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Stockholders' Equity and Derivative Liability - Warrants - Components of changes (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Number of Warrants Outstanding    
Balance at the beginning of the period (in shares) 102,642 107,998
Expiration of warrants (4,314) (5,356)
Balance at end of period (in shares) 10,714 102,642
Cumulative Effect, Period of Adoption, Adjustment    
Number of Warrants Outstanding    
Balance at the beginning of the period (in shares) 87,614  
Balance at end of period (in shares)   87,614
Warrants | (Level 3)    
Derivative Instrument Liability    
Balance at the beginning of the period $ (11,673) $ (5,623)
Change in fair value of warrants (11,673) 6,050
Balance at end of period $ 0 $ (11,673)