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Fair Value Measurements (Details)
1 Months Ended 3 Months Ended
Oct. 31, 2018
USD ($)
shares
Jun. 30, 2016
Mar. 31, 2020
USD ($)
Mar. 31, 2019
USD ($)
Dec. 31, 2019
USD ($)
Jun. 10, 2016
$ / shares
Fair value measurements            
Contingent consideration     $ 2,460,000   $ 2,430,000  
Change in fair value of contingent consideration            
Change in fair value of contingent consideration     30,000 $ 100,000    
Discount rate            
Change in fair value of contingent consideration            
Measurement Input           6.5
Share Price            
Change in fair value of contingent consideration            
Measurement Input | $ / shares           19.60
Ciclofilin            
Change in fair value of contingent consideration            
Payment of contingent consideration milestone $ 1,000,000          
Number of shares issued | shares 1,439          
Issuance of common stock in conjunction with milestone payment $ 55,398          
Percentage of issued and outstanding 2.50% 2.50%        
Level 3 | Contingent Consideration            
Change in fair value of contingent consideration            
Balance at beginning of the period     2,430,000      
Change in fair value recorded in earnings     30,000      
Balance at end of the period     2,460,000      
Recurring basis            
Fair value measurements            
Contingent consideration     2,460,000   2,430,000  
Derivative liabilities related to warrants     15,303   5,623  
Recurring basis | Level 3            
Fair value measurements            
Contingent consideration     2,460,000   2,430,000  
Derivative liabilities related to warrants     $ 15,303   $ 5,623