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Accounting for Share-Based Payments - Equity Incentive Plan (Details) - USD ($)
3 Months Ended 6 Months Ended
Jun. 03, 2013
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Accounting for Shared-Based Payments          
Vesting period (in years) 3 years        
Contractual term 10 years        
Authorized number of options (in shares)   1,337,500   1,337,500  
Common stock available for grant under the plan   485,268   485,268  
Stock based compensation expense          
Total stock based compensation expense   $ 152,764 $ 273,229 $ 370,151 $ 827,701
General and administrative          
Stock based compensation expense          
Total stock based compensation expense   120,759 272,693 308,415 601,242
Research and development          
Stock based compensation expense          
Total stock based compensation expense   $ 32,005 $ 536 $ 61,736 $ 226,459