<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: BIGGER CAPITAL FUND L P -->
          <cik>0001288478</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <securitiesClassTitle>Common Stock, $.0001 par value</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>01/21/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001583771</issuerCik>
        <issuerName>Hepion Pharmaceuticals, Inc.</issuerName>
        <issuerCusip>426897302</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>399 THORNALL STREET</com:street1>
          <com:street2>FIRST FLOOR</com:street2>
          <com:city>EDISON</com:city>
          <com:stateOrCountry>NJ</com:stateOrCountry>
          <com:zipCode>08837</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>BIGGER CAPITAL FUND L P</reportingPersonName>
      <memberGroup>a</memberGroup>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>1060883.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>1060883.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1060883.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>9.99</classPercent>
      <typeOfReportingPerson>PN</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Bigger Capital Fund GP, LLC</reportingPersonName>
      <memberGroup>a</memberGroup>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>1060883.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>1060883.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1060883.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>9.99</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Bigger Michael</reportingPersonName>
      <memberGroup>a</memberGroup>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>1060883.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>1060883.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1060883.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>9.99</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Hepion Pharmaceuticals, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>399 Thornall Street, First Floor, Edison, NJ 08837</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Bigger Capital Fund, LP ("Bigger Capital")

Bigger Capital Fund GP, LLC ("Bigger GP")

Michael Bigger

Each of the foregoing is referred to as a "Reporting Person" and collectively as the "Reporting Persons."</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>Bigger Capital Fund, LP
2250 Red Springs Drive
Las Vegas, NV 89135

Bigger Capital Fund GP, LLC
2250 Red Springs Drive
Las Vegas, NV 89135

Michael Bigger
2250 Red Springs Drive
Las Vegas, NV 89135</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Bigger Capital Fund, LP
Citizenship: Delaware

Bigger Capital Fund GP, LLC
Citizenship: Delaware

Michael Bigger
Citizenship: United States</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>As of January 23, 2025, Bigger Capital beneficially owned 1,060,883 shares of Common Stock which includes shares of the Issuer's Common Stock issuable upon the exercise of Pre-Funded Warrants the exercise of which is subject to a 9.99% beneficial ownership limitation.

The amounts do not include 994,958 shares and 994,958 shares issuable upon the exercise of Series A Warrants and Series B Warrants, respectively, the exercise of which are subject to shareholder approval and a 4.99% beneficiary ownership limitation. The percentage set forth on Row (11) of the cover page for the reporting person is based on 10,619,458 shares of Common Stock outstanding after the offering described in the Issuer's Prospectus filed under Rule 424(b)(4) with the Securities and Exchange Commission on January 23, 2025.

Bigger GP, as the general partner of Bigger Capital, may be deemed to beneficially own the Issuer's securities described herein.

Mr. Bigger, as the managing member of Bigger GP may be deemed to beneficially own the Issuer's securities described herein.

The foregoing should not be construed in and of itself as an admission by any Reporting Person as to beneficial ownership of any shares of Common Stock owned by another Reporting Person. Each of Bigger GP and Mr. Bigger disclaims beneficial ownership of the shares of Common Stock beneficially owned by Bigger Capital. The filing of this statement shall not be construed as an admission that any such person or entity is the beneficial owner of any such securities.

Regarding Item 5 below, subsequent to January 23, 2025, the Reporting Person sold 1,060,883 shares of Common Stock and accordingly, the Reporting Person as of January 24, 2025 does not own any securities of the Issuer (other than shares of Common Stock issuable upon exercise of Series A and Series B Warrants, the exercise of which are subject to shareholder approval and a 4.99% beneficial ownership limitation) and will not be amending this Schedule 13G.</amountBeneficiallyOwned>
        <classPercent>As of the close of business on January 23, 2025, each of Bigger Capital, Bigger GP, and Mr. Bigger may be deemed to beneficially own approximately 9.99% of the outstanding shares of Common Stock. Subsequent to January 23, 2025, each of Bigger Capital, Bigger GP and Mr. Bigger had no beneficial ownership due to the sale of 10,619,458 shares of Common Stock and the requirement in the Series A and Series B warrants that the exercise of such securities is subject to stockholder approval.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>See Cover Pages Items 5-9.</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>See Cover Pages Items 5-9.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>See Cover Pages Items 5-9.</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>See Cover Pages Items 5-9.</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>N</notApplicableFlag>
        <identificationAndClassificationOfGroupMembers>See Exhibit 99.1.</identificationAndClassificationOfGroupMembers>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <exhibitInfo>99.1 - Joint Filing Agreement</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>BIGGER CAPITAL FUND L P</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Michael Bigger</signature>
        <title>Michael Bigger, Managing Member of Bigger Capital Fund GP, LLC, its general partner</title>
        <date>01/24/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Bigger Capital Fund GP, LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Michael Bigger</signature>
        <title>Michael Bigger, Managing Member</title>
        <date>01/24/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Bigger Michael</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Michael Bigger</signature>
        <title>Michael Bigger</title>
        <date>01/24/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>

</edgarSubmission>
