CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (Unaudited) (Parenthetical) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Total share-based compensation expense	$ 6,262	$ 8,530	$ 19,547	$ 32,784
Research and development
Total share-based compensation expense	2,004	2,623	6,301	10,062
Selling, general and administrative
Total share-based compensation expense	$ 4,258	5,196	12,890	15,724
Restructuring and related expenses
Total share-based compensation expense		$ 711	$ 356	$ 6,998