CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands		3 Months Ended		6 Months Ended
		Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Revenue:
Total revenue		$ 13,749	$ 11,050	$ 24,166	$ 24,246
Expenses:
Research and development (1)	[1]	9,425	14,924	23,997	38,177
Selling, general and administrative (1)	[1]	19,278	16,222	38,461	34,064
Restructuring and related expenses (1)	[1]	1,169	3,005	2,743	12,329
Total expenses		29,872	34,151	65,201	84,570
Loss from operations		(16,123)	(23,101)	(41,035)	(60,324)
Interest expense		(568)	(2,137)	(1,118)	(4,274)
Interest income and other income (expense), net		2,504	2,440	5,483	2,065
Loss from continuing operations before income taxes		(14,187)	(22,798)	(36,670)	(62,533)
Provision for income tax (expense) benefit		(1,458)	5	(1,063)	(519)
Net loss from continuing operations		(15,645)	(22,793)	(37,733)	(63,052)
Income from discontinued operations before income taxes			14,602		28,915
Provision for income tax expense
Net income from discontinued operations			14,602		28,915
Net loss		(15,645)	(8,191)	(37,733)	(34,137)
Net unrealized loss on available-for-sale investments		(337)	(17)	(271)	(45)
Total comprehensive loss		$ (15,982)	$ (8,208)	$ (38,004)	$ (34,182)
Net income (loss) per share:
Continuing operations - basic		$ (0.28)	$ (0.30)	$ (0.63)	$ (0.83)
Continuing operations - diluted		(0.28)	(0.30)	(0.63)	(0.83)
Discontinued operations - basic			0.19		0.38
Discontinued operations - diluted			0.19		0.38
Net loss - basic		(0.28)	(0.11)	(0.63)	(0.45)
Net loss - diluted		$ (0.28)	$ (0.11)	$ (0.63)	$ (0.45)
Shares used to compute net income (loss) per share - basic		56,682	76,270	59,791	75,761
Shares used to compute net income (loss) per share - diluted		56,682	76,270	59,791	75,761
Total share-based compensation expense		$ 6,264	$ 9,709	$ 13,285	$ 24,254
Research and development
Expenses:
Restructuring and related expenses (1)		1,200	1,000	2,700	5,700
Net income (loss) per share:
Total share-based compensation expense		1,855	2,909	4,296	7,439
Selling, general and administrative
Expenses:
Restructuring and related expenses (1)			2,000		6,600
Net income (loss) per share:
Total share-based compensation expense		4,409	5,030	8,632	10,528
Restructuring and related expenses
Net income (loss) per share:
Total share-based compensation expense			1,770	357	6,287
Viatris collaboration agreement
Revenue:
Total revenue		13,743	10,878	24,154	21,565
Collaboration revenue
Revenue:
Total revenue		$ 6	$ 172	$ 12	181
Licensing revenue
Revenue:
Total revenue					$ 2,500

[1] Amounts include share-based compensation expense as follows: