CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands		3 Months Ended
		Mar. 31, 2023	Mar. 31, 2022
Revenue:
Total revenue		$ 10,417	$ 13,196
Expenses:
Research and development (1)	[1]	14,572	23,253
Selling, general and administrative (1)	[1]	19,183	17,842
Restructuring and related expenses (1)	[1]	1,574	9,324
Total expenses		35,329	50,419
Loss from operations		(24,912)	(37,223)
Interest expense		(550)	(2,137)
Interest income and other income (expense), net		2,979	(375)
Loss from continuing operations before income taxes		(22,483)	(39,735)
Provision for income tax benefit (expense)		395	(524)
Net loss from continuing operations		(22,088)	(40,259)
Income from discontinued operations before income taxes			14,313
Provision for income tax expense		(400)
Net income from discontinued operations			14,313
Net loss		(22,088)	(25,946)
Net unrealized gain (loss) on marketable securities		66	(28)
Total comprehensive loss		$ (22,022)	$ (25,974)
Net income (loss) per share:
Continuing operations - basic		$ (0.35)	$ (0.53)
Continuing operations - diluted		(0.35)	(0.53)
Discontinued operations - basic			0.19
Discontinued operations - diluted			0.19
Net income (loss) - basis		(0.35)	(0.34)
Net income (loss) - diluted		$ (0.35)	$ (0.34)
Shares used to compute basis and diluted net income (loss) per share		62,934	75,247
Shares used to compute basis and diluted net income (loss) per share		62,934	75,247
Total share-based compensation expense		$ 7,021	$ 14,545
Research and development
Expenses:
Restructuring and related expenses (1)			4,700
Net income (loss) per share:
Total share-based compensation expense		2,441	4,530
Selling, general and administrative
Expenses:
Restructuring and related expenses (1)			4,600
Net income (loss) per share:
Total share-based compensation expense		4,223	5,498
Restructuring and related expenses
Net income (loss) per share:
Total share-based compensation expense		357	4,517
Viatris collaboration agreement
Revenue:
Total revenue		10,411	10,687
Collaboration revenue
Revenue:
Total revenue		$ 6	9
Licensing revenue
Revenue:
Total revenue			$ 2,500

[1] Amounts include share-based compensation expense as follows: