Investments and Fair Value Measurements - Available-for-sale securities (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Available for sale securities:
Amortized Cost	$ 241,327	$ 303,557
Gross Unrealized Gains	79	12
Gross Unrealized Losses	(28)	(27)
Estimated Fair Value	241,378	303,542
Debt Securities, Available-for-sale, Unrealized Gain (Loss) [Abstract]
Estimated Fair Value lesser than 12 months	45,885	37,279
Fair value of assets transferred from Level 1 to Level 2	0
Fair value of assets transferred from Level 2 to Level 1	0
Estimated Fair Value Total	45,885	37,279
Gross unrealized lesser than 12 months	(28)	(27)
Gross unrealized loss, Total	(28)	(27)
Marketable securities
Available for sale securities:
Amortized Cost	92,211	83,049
Gross Unrealized Gains	79	12
Gross Unrealized Losses	(28)	(27)
Estimated Fair Value	92,262	83,034
U.S. government securities
Debt Securities, Available-for-sale, Unrealized Gain (Loss) [Abstract]
Estimated Fair Value lesser than 12 months	14,525
Estimated Fair Value Total	14,525
Gross unrealized lesser than 12 months	(6)
Gross unrealized loss, Total	(6)
U.S. government securities \| Quoted Prices in Active Markets for Identical Assets, Level 1
Available for sale securities:
Amortized Cost	29,119	24,873
Gross Unrealized Gains	6	8
Gross Unrealized Losses	(6)
Estimated Fair Value	29,119	24,881
U.S. corporate notes
Debt Securities, Available-for-sale, Unrealized Gain (Loss) [Abstract]
Estimated Fair Value lesser than 12 months	16,434
Estimated Fair Value Total	16,434
Gross unrealized lesser than 12 months	(20)
Gross unrealized loss, Total	(20)
U.S. corporate notes \| Significant Other Observable Inputs, Level 2
Available for sale securities:
Amortized Cost	38,906
Gross Unrealized Gains	63
Gross Unrealized Losses	(20)
Estimated Fair Value	38,949
U.S. commercial paper
Debt Securities, Available-for-sale, Unrealized Gain (Loss) [Abstract]
Estimated Fair Value lesser than 12 months	14,926	37,279
Estimated Fair Value Total	14,926	37,279
Gross unrealized lesser than 12 months	(2)	(27)
Gross unrealized loss, Total	(2)	(27)
U.S. commercial paper \| Significant Other Observable Inputs, Level 2
Available for sale securities:
Amortized Cost	14,927	37,307
Gross Unrealized Losses	(2)	(27)
Estimated Fair Value	14,925	37,280
U.S. government agency securities \| Significant Other Observable Inputs, Level 2
Available for sale securities:
Amortized Cost	9,259	20,869
Gross Unrealized Gains	10	4
Estimated Fair Value	9,269	20,873
Money market funds \| Quoted Prices in Active Markets for Identical Assets, Level 1
Available for sale securities:
Amortized Cost	149,116	220,508
Estimated Fair Value	$ 149,116	$ 220,508

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