Corporate Restructuring Completion (Details) - USD ($) $ in Thousands		1 Months Ended	12 Months Ended
	Sep. 15, 2021	Sep. 30, 2022	Dec. 31, 2022	Dec. 31, 2021
Corporate Restructuring
Reduction in workforce (as a percent)	75.00%
Restructuring costs		$ 33,000	$ 12,838	$ 20,142
Research and development
Corporate Restructuring
Restructuring costs		16,500	5,900	10,600
Selling, general and administrative
Corporate Restructuring
Restructuring costs		16,500	6,900	9,500
Severance
Corporate Restructuring
Restructuring costs		33,000
Employee-related separation costs			12,800	20,100
Cash charges related to modification of equity-awards for terminated and remaining employee		17,400	5,800	11,500
Non-cash charges related to modification of equity-awards for terminated and remaining employee		$ 15,600	$ 7,000	$ 8,600