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Capital Return Program (Details) - USD ($)
1 Months Ended 12 Months Ended
Nov. 22, 2022
Nov. 21, 2022
Sep. 28, 2022
Sep. 20, 2022
Feb. 28, 2023
Jan. 31, 2023
Feb. 28, 2022
Jan. 31, 2022
Dec. 31, 2022
Sep. 30, 2022
Dec. 31, 2021
Capital Return Program                      
Share repurchase authorized amount                   $ 250,000,000.0  
Ordinary shares, par value (in dollars per share)                 $ 0.00001   $ 0.00001
Consideration for repurchase                 $ 128,830,000    
Ordinary shares, shares issued                 65,227,000   74,435,000
Ordinary shares, shares outstanding                 65,227,000   74,435,000
Aggregate cost                 $ 128,830,000    
GSK Share Repurchase                      
Capital Return Program                      
Share repurchase authorized amount                   $ 250,000,000.0  
Shares authorized to be repurchased (in shares)       9,644,807              
Ordinary shares, par value (in dollars per share)       $ 0.00001              
Repurchase price (in dollars per share)       $ 9.75              
Consideration for repurchase       $ 94,000,000.0              
Ordinary shares, shares outstanding       0              
Modified Dutch Auction Tender Offer                      
Capital Return Program                      
Share repurchase authorized amount     $ 95,000,000.0                
Repurchase price (in dollars per share) $ 10.50                    
Share repurchase (as a percent)   0.20%                  
Aggregate cost $ 1,200,000                    
Repurchase of ordinary shares (in shares) 115,967 115,967                  
Modified Dutch Auction Tender Offer | Minimum                      
Capital Return Program                      
Repurchase price (in dollars per share)     $ 9.75                
Modified Dutch Auction Tender Offer | Maximum                      
Capital Return Program                      
Repurchase price (in dollars per share)     $ 10.50                
Open Market Share Repurchase Plan                      
Capital Return Program                      
Repurchase price (in dollars per share)         $ 10.99 $ 10.99     $ 11.06    
Aggregate cost         $ 27,100,000 $ 27,100,000     $ 32,900,000    
Repurchase of ordinary shares (in shares)             2,461,000 2,461,000 2,978,341