Extinguishment of Debt (Details) - USD ($) $ in Thousands				1 Months Ended	12 Months Ended
	Jul. 26, 2022	Jul. 20, 2022	Feb. 21, 2020	Nov. 30, 2016	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Debt Instrument [Line Items]
Accrued interest						$ 1,246
Loss on extinguishment of debt					$ (3,034)
Total long-term debt						616,334
Stated coupon interest					4,859	7,475	$ 7,475
Amortization of debt issuance costs					536	1,072	1,072
Ampreloxetine interest accretion					974
Total debt interest expense					$ 6,369	$ 8,547	8,547
9.5% Non-Recourse 2035 Notes
Debt Instrument [Line Items]
Interest rate (as a percent)			9.50%		9.50%	9.50%
Principal amount			$ 400,000			$ 413,291
Percentage of note to be sold			95.00%
Percentage of note to be retained			5.00%
Accrued interest		$ 4,700
Early redemption premium fee		20,000
Transaction costs		200
Net interest shortfall		30,700
Loss on extinguishment of debt		(24,000)
Less: 5% retained by the Company						(20,665)
Unamortized debt issuance costs						(3,062)
Total long-term debt						388,299
Net principal						392,600
Estimated fair value						373,000
Principal payment on notes		$ 400,000			$ 399,998	$ 10,730	$ 235,347
9.0% Non-Recourse 2033 Notes
Debt Instrument [Line Items]
Interest rate (as a percent)					9.00%	9.00%
Unamortized debt issuance costs						$ (1,265)
3.25% Convertible Senior Notes Due 2023
Debt Instrument [Line Items]
Proceeds from issuance of debt				$ 222,500
Interest rate (as a percent)				3.25%		3.25%
Principal amount				$ 230,000		$ 230,000
Accrued interest	$ 2,400
Transaction costs				$ 7,500
Loss on extinguishment of debt	3,000
Retirement of debt	$ 230,000
Debt retired (as percent)	100.00%
Unamortized debt issuance costs						(1,965)
Total long-term debt						228,035
Transaction costs	$ 1,600
Principal payment on notes					$ 231,605
3.25% Convertible Senior Notes Due 2023 | Significant Other Observable Inputs, Level 2
Debt Instrument [Line Items]
Net principal						230,000
Notes fair value						$ 220,200
TRC
Debt Instrument [Line Items]
Percentage of equity interest						85.00%
Percentage of economic interest			85.00%			85.00%
TRC | Minimum
Debt Instrument [Line Items]
Upward tiering royalties (as a percent)			6.50%
TRC | Maximum
Debt Instrument [Line Items]
Upward tiering royalties (as a percent)			10.00%
Theravance Biopharma R&D, Inc. | 9.5% Non-Recourse 2035 Notes
Debt Instrument [Line Items]
Interest rate (as a percent)						5.00%