Investments and Fair Value Measurements - Available-for-sale securities (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Available for sale securities:
Amortized Cost	$ 303,557	$ 133,738
Gross Unrealized Gains	12	1
Gross Unrealized Losses	(27)	(5)
Estimated Fair Value	303,542	133,734
Debt Securities, Available-for-sale, Unrealized Gain (Loss) [Abstract]
Estimated Fair Value lesser than 12 months	37,279	35,017
Fair value of assets transferred from Level 1 to Level 2	0
Fair value of assets transferred from Level 2 to Level 1	0
Estimated Fair Value Total	37,279	35,017
Gross unrealized lesser than 12 months	(27)	(5)
Gross unrealized loss, Total	(27)	(5)
Marketable securities
Available for sale securities:
Amortized Cost	83,049	83,510
Gross Unrealized Gains	12	1
Gross Unrealized Losses	(27)	(5)
Estimated Fair Value	83,034	83,506
U.S. government securities
Debt Securities, Available-for-sale, Unrealized Gain (Loss) [Abstract]
Estimated Fair Value lesser than 12 months		19,991
Estimated Fair Value Total		19,991
Gross unrealized lesser than 12 months		(2)
Gross unrealized loss, Total		(2)
U.S. government securities \| Quoted Prices in Active Markets for Identical Assets, Level 1
Available for sale securities:
Amortized Cost	24,873	29,986
Gross Unrealized Gains	8
Gross Unrealized Losses		(2)
Estimated Fair Value	24,881	29,984
U.S. corporate notes
Debt Securities, Available-for-sale, Unrealized Gain (Loss) [Abstract]
Estimated Fair Value lesser than 12 months		5,031
Estimated Fair Value Total		5,031
Gross unrealized lesser than 12 months		(2)
Gross unrealized loss, Total		(2)
U.S. corporate notes \| Significant Other Observable Inputs, Level 2
Available for sale securities:
Amortized Cost		5,034
Gross Unrealized Losses		(2)
Estimated Fair Value		5,032
U.S. commercial paper
Debt Securities, Available-for-sale, Unrealized Gain (Loss) [Abstract]
Estimated Fair Value lesser than 12 months	37,279	9,995
Estimated Fair Value Total	37,279	9,995
Gross unrealized lesser than 12 months	(27)	(1)
Gross unrealized loss, Total	(27)	(1)
U.S. commercial paper \| Significant Other Observable Inputs, Level 2
Available for sale securities:
Amortized Cost	37,307	48,490
Gross Unrealized Gains		1
Gross Unrealized Losses	(27)	(1)
Estimated Fair Value	37,280	48,490
U.S. government agency securities \| Significant Other Observable Inputs, Level 2
Available for sale securities:
Amortized Cost	20,869
Gross Unrealized Gains	4
Estimated Fair Value	20,873
Money market funds \| Quoted Prices in Active Markets for Identical Assets, Level 1
Available for sale securities:
Amortized Cost	220,508	50,228
Estimated Fair Value	$ 220,508	$ 50,228

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