The amount of upfront payments receivable under the collaboration arrangement.

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Revenue earned under collaborative arrangements from upfront payments and contingent payments.

+ References

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- Definition

Represents the percentage of profit or loss sharing arrangement as per collaboration agreement.

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+ References

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Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

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Revenue - Viatris Agreement (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended	12 Months Ended
	Feb. 28, 2018	Dec. 31, 2022	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Collaborative Arrangements and Co-Promote Agreement
Percentage of profit share			35.00%
Upfront payment receivable			$ 205,000
Collaboration revenue
Collaborative Arrangements and Co-Promote Agreement
Revenues			48,654	$ 43,848	$ 43,893
Revenue from collaborative arrangements			192	11,463	26,464
Revefenacin Monotherapy (TD-4208)
Collaborative Arrangements and Co-Promote Agreement
Upfront payment receivable			160,000
Revefenacin Monotherapy (TD-4208) \| Success Based Development Regulatory And Sales Milestones
Collaborative Arrangements and Co-Promote Agreement
Upfront payment receivable			10,000
Revefenacin Monotherapy (TD-4208) \| Sales milestones
Collaborative Arrangements and Co-Promote Agreement
Upfront payment receivable			150,000
Future potential combination products
Collaborative Arrangements and Co-Promote Agreement
Upfront payment receivable			45,000
YUPELRI Monotherapy
Collaborative Arrangements and Co-Promote Agreement
Upfront payment receivable			$ 160,000
Janssen
Collaborative Arrangements and Co-Promote Agreement
Revenue from collaborative arrangements				11,425	26,426
Janssen \| Development and Commercialization Agreement
Collaborative Arrangements and Co-Promote Agreement
Upfront payment receivable	$ 100,000
Viatris
Collaborative Arrangements and Co-Promote Agreement
Percentage of profit share			65.00%
Viatris \| YUPELRI Monotherapy
Collaborative Arrangements and Co-Promote Agreement
Percentage of profit share			35.00%
Revenues			$ 70,700	56,700	50,000
Viatris \| Non-US YUPELRI
Collaborative Arrangements and Co-Promote Agreement
Royalty Income		$ 30,000
Viatris \| Collaborative Arrangement \| Collaboration revenue
Collaborative Arrangements and Co-Promote Agreement
Revenues			48,624	43,848	43,893
Viatris \| Royalties (Non-US) \| Collaboration revenue
Collaborative Arrangements and Co-Promote Agreement
Revenues			30
Other
Collaborative Arrangements and Co-Promote Agreement
Revenue from collaborative arrangements			$ 192	$ 38	$ 38