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Organization and Summary of Significant Accounting Policies - Net Loss per Share - Anti-dilutive (Details) - shares
shares in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Anti-Dilutive Securities      
Anti-dilutive securities (in shares) 5,487 14,145 13,229
Share issuances under equity incentive plans and employee share purchase plans      
Anti-Dilutive Securities      
Anti-dilutive securities (in shares) 5,487 7,469 6,553
Share issuances upon the conversion of convertible senior notes      
Anti-Dilutive Securities      
Anti-dilutive securities (in shares)   6,676 6,676