Organization and Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2022

Organization and Summary of Significant Accounting Policies.

Schedule of property and equipment useful lives

Leasehold improvements	Shorter of remaining lease terms or useful life
Equipment, furniture and fixtures	5 - 7 years
Software and computer equipment	3 - 5 years

Schedule of basic and diluted net income (loss) per share

	Year Ended December 31,
(In thousands, except per share data)	2022		2021		2020
Numerator:
Net loss from continuing operations	$	(92,824)	$	(265,071)	$	(294,823)
Net income from discontinued operations		964,956		65,645		16,806
Net income (loss)		872,132		(199,426)		(278,017)
Denominator:
Weighted-average ordinary shares outstanding		73,591		69,518		62,808
Less: weighted-average ordinary shares subject to forfeiture		—		(57)		(463)
Weighted-average ordinary shares outstanding - basic and diluted		73,591		69,461		62,345
Net income (loss) per ordinary share:
Continuing operations - basic and diluted	$	(1.26)	$	(3.82)	$	(4.73)
Discontinued operations - basic and diluted	$	13.11	$	0.95	$	0.27
Net income (loss) - basic and diluted	$	11.85	$	(2.87)	$	(4.46)

Schedule of anti-dilutive securities

	Year Ended December 31,
(In thousands)	2022	2021	2020
Share issuances under equity incentive plans and employee share purchase plans	5,487	7,469	6,553
Share issuances upon the conversion of convertible senior notes	—	6,676	6,676
Total	5,487	14,145	13,229