CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenue:
Total revenue	$ 12,451	$ 13,194	$ 36,697	$ 40,365
Expenses:
Research and development (1)	9,867	43,739	48,691	162,431
Selling, general and administrative (1)	16,277	21,299	51,105	77,780
Restructuring and related expenses (1)	509	1,771	11,427	1,771
Total expenses	26,653	66,809	111,223	241,982
Loss from operations	(14,202)	(53,615)	(74,526)	(201,617)
Interest expense	(1,545)	(2,136)	(5,819)	(6,410)
Loss on extinguishment of debt	(3,034)		(3,034)
Interest income and other income (expense), net	2,758	(166)	4,823	771
Loss from continuing operations before income taxes	(16,023)	(55,917)	(78,556)	(207,256)
Provision for income tax benefit (expense)		7	(12)
Net loss from continuing operations	(16,023)	(55,910)	(78,568)	(207,256)
Income from discontinued operations before income taxes	1,115,016	20,602	1,143,930	39,864
Provision for income tax expense	(182,362)		(182,868)
Net income from discontinued operations	932,654	20,602	961,062	39,864
Net income (loss)	916,631	(35,308)	882,494	(167,392)
Net unrealized gain (loss) on available-for-sale investments	(76)	6	(121)	(33)
Total comprehensive income (loss)	$ 916,555	$ (35,302)	$ 882,373	$ (167,425)
Net income (loss) per share:
Continuing operations - basic	$ (0.21)	$ (0.76)	$ (1.04)	$ (3.05)
Continuing operations - diluted	(0.21)	(0.76)	(1.04)	(3.05)
Discontinued operations - basic	12.35	0.28	12.70	0.59
Discontinued operations - diluted	12.35	0.28	12.70	0.59
Net income (loss) - basis	12.14	(0.48)	11.66	(2.46)
Net income (loss) - diluted	$ 12.14	$ (0.48)	$ 11.66	$ (2.46)
Shares used to compute basic net income (loss) per share	75,515	73,574	75,678	67,945
Shares used to compute diluted net income (loss) per share	75,515	73,574	75,678	67,945
Total share-based compensation expense	$ 8,530	$ 14,370	$ 32,784	$ 45,143
Research and development
Expenses:
Restructuring and related expenses (1)	100		5,300
Net income (loss) per share:
Total share-based compensation expense	2,623	6,956	10,709	22,192
Selling, general and administrative
Expenses:
Restructuring and related expenses (1)	400		6,200
Net income (loss) per share:
Total share-based compensation expense	5,196	7,414	16,488	22,951
Restructuring and related expenses
Net income (loss) per share:
Total share-based compensation expense	711		5,587
Viatris collaboration agreement
Revenue:
Total revenue	12,445	10,397	34,010	31,716
Collaboration revenue
Revenue:
Total revenue	$ 6	$ 2,797	187	$ 8,649
Licensing revenue
Revenue:
Total revenue			$ 2,500