Leases (Details) $ in Thousands	1 Months Ended		3 Months Ended	6 Months Ended
	Jun. 30, 2022 USD ($) ft²	May 31, 2022 USD ($) ft²	Jun. 30, 2022 USD ($) ft²	Jun. 30, 2022 USD ($) ft²	Jun. 30, 2021 USD ($)	Apr. 30, 2017 ft²
Lessee, Lease, Description [Line Items]
Decrease in operating lease liabilities				$ (82)	$ (1,718)
Gain on lease modification				47
Sublease
Lessee, Lease, Description [Line Items]
Expects to receive base rent	$ 51,839		$ 51,839	$ 51,839
Dublin
Lessee, Lease, Description [Line Items]
Area of leased space | ft²		700				6,100
Decrease in operating lease assets		$ 1,400
Decrease in operating lease liabilities		1,500
Loss on sale of furniture and equipment		100
Operating lease expenses		$ 400
Option to terminate		true
Lease term		2 years
Lease termination notice period		3 months
South San Francisco
Lessee, Lease, Description [Line Items]
Area of subleased property | ft²	78,000		78,000	78,000
South San Francisco | Sublease
Lessee, Lease, Description [Line Items]
Option to terminate sublease	false
Monthly base rent	$ 500
Increase in annual base rent (as a percent)	3.00%
Expected sublease income			$ 300	$ 300
Premium component in sublease income	$ 13,600
Percentage of excess sublease income over lease obligations received to be shared with lessor	50.00%
Premium component in sublease income to be shared with lessor	$ 6,800
Percentage of excess sublease income over lease obligations to be retained	50.00%
Expects to receive base rent	$ 51,800		$ 51,800	$ 51,800