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Share-Based Compensation - Share Based Compensation Expense By Type (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share-Based Compensation      
Total share-based compensation expense $ 62,061 $ 62,976 $ 60,450
Unrecognized compensation cost 93,551    
Stock options      
Share-Based Compensation      
Total share-based compensation expense 5,473 6,536 6,381
Unrecognized compensation cost $ 4,535    
Weighted-average amortization period - years 1 year 11 months 23 days    
RSUs      
Share-Based Compensation      
Total share-based compensation expense $ 54,931 49,803 39,520
Unrecognized compensation cost $ 88,220    
Weighted-average amortization period - years 2 years 9 months 7 days    
Performance-Contingent Awards - RSAs and RSUs      
Share-Based Compensation      
Total share-based compensation expense $ 763 3,943 12,717
Unrecognized compensation cost $ 795    
Weighted-average amortization period - years 2 years 4 months 13 days    
ESPP      
Share-Based Compensation      
Total share-based compensation expense $ 894 $ 2,694 1,768
Unrecognized compensation cost $ 1    
Weighted-average amortization period - years 8 months 12 days    
Theravance | RSAs      
Share-Based Compensation      
Total share-based compensation expense     $ 64